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Merck
CN

02010595

缬草烯酸

primary reference standard

别名:

(2E)-3-[(4S,7R,7aR)-2,4,5,6,7,7a-六氢-3,7-二甲基-1H-茚-4-基]-2-甲基-2-丙烯酸

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关于此项目

经验公式(希尔记法):
C15H22O2
化学文摘社编号:
分子量:
234.33
Beilstein:
3138020
MDL编号:
UNSPSC代码:
85151701
PubChem化学物质编号:
NACRES:
NA.24
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等级

primary reference standard

保质期

limited shelf life, expiry date on the label

制造商/商品名称

HWI

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

food and beverages

SMILES字符串

[H][C@]12CCC(C)=C1[C@@H](CC[C@H]2C)\C=C(/C)C(O)=O

InChI

1S/C15H22O2/c1-9-4-6-12(8-11(3)15(16)17)14-10(2)5-7-13(9)14/h8-9,12-13H,4-7H2,1-3H3,(H,16,17)/b11-8+/t9-,12+,13-/m1/s1

InChI key

FEBNTWHYQKGEIQ-SUKRRCERSA-N

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相关类别

一般描述

Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

应用

草药产品分析的标准品。

其他说明

This compound is commonly found in plants of the genus: valeriana

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Chethan Sampath et al.
Planta medica, 78(6), 575-581 (2012-03-14)
Valerenic acid (VA), a sesquiterpenoid, is one of the major secondary bioactive metabolites of VALERIANA OFFICINALIS L. Until now IN VIVO studies on the absorption, bioavailability, disposition, and metabolism of VA are limited. We established and validated an LC-MS/MS assay
S Khom et al.
British journal of pharmacology, 161(1), 65-78 (2010-08-20)
Subunit-specific modulators of gamma-aminobutyric acid (GABA) type A (GABA(A)) receptors can help to assess the physiological function of receptors with different subunit composition and also provide the basis for the development of new drugs. Valerenic acid (VA) was recently identified
Andres Navarrete et al.
Journal of AOAC International, 89(1), 8-15 (2006-03-04)
The roots and rhizomes of various valeriana species are currently used as a sleeping aid or mild sedative. A liquid chromatography method has been developed that permits the analysis of chlorogenic acid, lignans, flavonoids, valerenic acids, and valpotrates in various
Jürgen Ramharter et al.
Organic letters, 11(5), 1151-1153 (2009-01-31)
The first total synthesis of the sesquiterpenoid valerenic acid, a constituent of Valeriana officinalis, is described. The compound is a potent modulator of the GABA(A) receptor and may thus be useful in the treatment of various dysfunctions of the central
Juergen Ramharter et al.
Organic letters, 13(19), 5310-5313 (2011-09-08)
A mild and selective one-pot procedure to provide 2,4-dienols from simple cycloalkenones in high yields is described. This transformation is based on the in situ formation of acid-labile allylic alcohols, which on treatment with trifluoroacetic acid undergo a formal [1,3]-hydroxy

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