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Merck
CN

02191

己二酸二酰肼

purum, ≥97.0% (NT)

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线性分子式:
NH2NHCO(CH2)4CONHNH2
化学文摘社编号:
分子量:
174.20
EC Number:
213-999-5
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
973863
MDL number:
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grade

purum

assay

≥97.0% (NT)

mp

180-182 °C

SMILES string

NNC(=O)CCCCC(=O)NN

InChI

1S/C6H14N4O2/c7-9-5(11)3-1-2-4-6(12)10-8/h1-4,7-8H2,(H,9,11)(H,10,12)

InChI key

IBVAQQYNSHJXBV-UHFFFAOYSA-N

Application

Adipic acid dihydrazide can be used to study chemical synthesis, organic building blocks, carbonyl compounds and hydrazides. Adipic acid dihydrazide has been used in a study to show that diphtheria toxoid can be successfully employed as a carrier protein for conjugation with Salmonella O-specific polysaccharides and play an important role in facilitating adequate immune response in typhoid fever vaccines. Adipic acid dihydrazide has also been used in a study to assess the activity of the derivatives of glycoside steviolbioside from the plant Stevia rebaudiana.

Other Notes

Bifunctional linker employed for the immobilization of carbohydrates, e.g. to MMAC resins (methyl vinyl ether, maleic anhydride co-polymer)


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pictograms

Environment

hcodes

Hazard Classifications

Aquatic Chronic 2

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

302.0 °F - closed cup

flash_point_c

150 °C - closed cup

ppe

Eyeshields, Gloves, type N95 (US)

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A Satoh et al.
Analytical biochemistry, 275(2), 231-235 (1999-12-20)
The immobilization of carbohydrates for solid-phase assays, including enzyme-linked immunosorbent assay (ELISA), is difficult because they are hydrophilic. We developed four new methods for the immobilization of oligosaccharides. ELISA plates were first coated with methyl vinyl ether-maleic anhydride copolymer (MMAC)
A Satoh et al.
Analytical biochemistry, 260(1), 96-102 (1998-07-02)
We have previously reported a method to immobilize protein ligands on microtiter plates coated with methyl vinyl ether-maleic anhydride copolymer (MMAC) [Isosaki, K., et al. (1992) J. Chromatogr. 597, 123-128]. In this study, we improved the MMAC method to efficiently
Anupam Basu et al.
Clinica chimica acta; international journal of clinical chemistry, 366(1-2), 287-292 (2005-12-13)
In hapten enzyme immunoassays (EIA), there is an increase or decrease of labeled hapten recognition by antibody that affects sensitivity of the assay. We incorporated a spacer between a hapten derivative and enzyme to test its influence on the sensitivity



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M13203-5G04061834038146