03394
聚（乙二醇）
tested according to Ph. Eur., 6,000
别名:
Macrogol 6,000, PEG
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关于此项目
线性分子式:
H(OCH2CH2)nOH
化学文摘社编号:
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352104
MDL number:
agency
tested according to Ph. Eur.
Quality Level
form
solid
mol wt
5000-7000
greener alternative product characteristics
Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.
sustainability
Greener Alternative Product
solubility
aliphatic hydrocarbons: slightly soluble, organic solvents: soluble
application(s)
pharmaceutical (small molecule)
greener alternative category
InChI
1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
InChI key
LYCAIKOWRPUZTN-UHFFFAOYSA-N
General description
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. Polyethylene glycol (PEG) is an eco-friendly, biodegradable polymer widely used in pharmaceuticals and cosmetics. Its non-toxic nature and versatility make it a sustainable choice, derived from renewable resources, contributing to greener product formulations. Click here for more information.
Application
聚乙二醇用于将西罗莫司固体分散体纳米粒作为亲水性载体进行表征。
Biochem/physiol Actions
聚乙二醇 (PEG) 是环氧乙烷和水的缩聚物。增强提取蛋白的复性。 这使得结晶蛋白的表征成为可能。
Preparation Note
聚乙二醇可溶于许多有机溶剂，易溶于芳香烃。也微溶于脂肪烃。
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存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
J L Cleland et al.
The Journal of biological chemistry, 267(19), 13327-13334 (1992-07-05)
Polyethylene glycol (PEG) inhibited aggregation during refolding of bovine carbonic anhydrase B (CAB) through the formation of a nonassociating PEG-intermediate complex. Stoichiometric concentrations of PEG were required for complete recovery of active protein during refolding at aggregating conditions. For example
J L Cleland et al.
Bio/technology (Nature Publishing Company), 10(9), 1013-1019 (1992-09-01)
Previous studies on the refolding of recombinant bovine carbonic anhydrase B (CAB) indicated that polyethylene glycol (PEG) significantly enhanced the recovery of active protein by reducing aggregation. To further test the ability of PEG to enhance refolding, three recombinant human
Min-Soo Kim et al.
International journal of nanomedicine, 6, 2997-3009 (2011-12-14)
The aim of this study was to improve the physicochemical properties and bioavailability of poorly water-soluble sirolimus via preparation of a solid dispersion of nanoparticles using a supercritical antisolvent (SAS) process. First, excipients for enhancing the stability and solubility of
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 206253-1G | 04061826741061 |
| 03394-1KG | 04061838618443 |