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04573

硫胺 盐酸盐

tested according to Ph. Eur.

别名:

盐酸硫胺素, 硫胺素 盐酸盐, 维生素 B 1 盐酸盐

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关于此项目

经验公式（希尔记法）:
C12H17ClN4OS · HCl
化学文摘社编号:
67-03-8
分子量:
337.27
NACRES:
NA.26
PubChem Substance ID:
329747946
eCl@ss:
34058006
UNSPSC Code:
12352209
EC Number:
200-641-8
MDL number:
MFCD00012780
Beilstein/REAXYS Number:
3851771
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biological source

synthetic

Quality Level

200

agency

tested according to Ph. Eur.

assay

98.5-101.0% anhydrous basis

form

solid

mp

250 °C (dec.) (lit.)

solubility

alcohol: soluble 1 gm in 100 ml (95%), alcohol: soluble 1 gm in 315 ml (Absolute), glycerol: soluble 1 gm in 18 ml, water: soluble 1 g/mL, benzene: insoluble, chloroform: insoluble, diethyl ether: insoluble, hexane: insoluble, methanol: very soluble, propylene glycol: soluble

storage temp.

2-8°C

SMILES string

CC1=NC(N)=C(C[N+]2=CSC(CCO)=C2C)C=N1.Cl.[Cl-]

InChI

1S/C12H17N4OS.2ClH/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13;;/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15);2*1H/q+1;;/p-1

InChI key

DPJRMOMPQZCRJU-UHFFFAOYSA-M

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相关类别

Application

Thiamine hydrochloride has been used as a keratin salts medium supplement for culturing log-phase fungus. It has also been used as a supplement of VB medium the minimal medium of Vogel and Bonner.

Biochem/physiol Actions

Thiamine hydrochloride is a hydrochloride salt form of thiamine (Vitamin B1). It is crucial for aerobic metabolism, cell growth, transmission of nerve impulses and acetylcholine synthesis.
Thiamine hydrochloride is a cheap, non-toxic and efficient catalyst for the synthesis of amidoalkyl naphthols. It inhibits the production of shikonin derivatives by suspension cultures of Lithospermum erythrorhizon. Additionally, thiamine hydrochloride addition to apple juice concentrates reduces its patulin content.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H319

Hazard Classifications

Eye Irrit. 2

存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCP0977
BCCN6320
BCCM9897
BCCM2433
BCCL4289

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Y Fujita et al.
Plant cell reports, 1(2), 61-63 (1981-12-01)
An excellent new medium was developed for the production of shikonin derivatives by suspension cultures of Lithospermum erythrorhizon. We investigated the effects of all the components of White's medium on the production of these derivatives. Nitrate, phosphate, copper, sulfate and
Thiamine hydrochloride as an efficient catalyst for the synthesis of amidoalkyl naphthols.
Min Lei
Tetrahedron Letters, 50, 6393-6397 (2009)
Thermodynamics of (solute+ solute) and (solute+ solvent) interactions of homologous series of amino acids with thiamine hydrochloride in aqueous medium at T=(305.15, 310.15, 315.15) K: A volumetric and acoustic approach
Kumar H and Behal I
The Journal of Chemical Thermodynamics, 102, 48-62 (2016)
G Apodaca et al.
Infection and immunity, 57(10), 3081-3090 (1989-10-01)
Trichophyton rubrum is the most common dermatophyte of humans and normally colonizes the superficial layers of the epidermis (stratum corneum). Several proteinases with a possible role in the metabolism of host proteins have been purified from this fungus. The regulation
Serafettin Yazici et al.
Die Nahrung, 46(4), 256-257 (2002-09-13)
Thiamine hydrochloride, pyridoxine hydrochloride and calcium-d-pantothenate were applied apple juice concentrates (AJC) at various doses in order to reduce the patulin content. AJC samples containing high levels of patulin were stored at 22 +/- 2 degrees C and 4 degrees
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货号GTIN
W358401-1KG-K04061837800993
W358401-SAMPLE-K04061837536946
01984-250MG04061838611802
P8602-5G04061837330506
W358401-100G-K04061837800986
04573-50G-F04061838633767

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