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Merck
CN

04573

Sigma-Aldrich

硫胺 盐酸盐

tested according to Ph. Eur.

别名:

盐酸硫胺素, 硫胺素 盐酸盐, 维生素 B 1 盐酸盐

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关于此项目

经验公式（希尔记法）:
C12H17ClN4OS · HCl
CAS Number:
67-03-8
分子量:
337.27
Beilstein:
3851771
EC 号:
200-641-8
MDL编号:
MFCD00012780
UNSPSC代码:
12352209
eCl@ss:
34058006
PubChem化学物质编号:
329747946
NACRES:
NA.26

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生物来源

synthetic

质量水平

200

Agency

USP/NF
tested according to Ph. Eur.

方案

98.5-101.0% anhydrous basis

表单

solid

mp

250 °C (dec.) (lit.)

溶解性

alcohol: soluble 1 gm in 100 ml (95%)
alcohol: soluble 1 gm in 315 ml (Absolute)
glycerol: soluble 1 gm in 18 ml
water: soluble 1 g/mL
benzene: insoluble
chloroform: insoluble
diethyl ether: insoluble
hexane: insoluble
methanol: very soluble
propylene glycol: soluble

储存温度

2-8°C

SMILES字符串

CC1=NC(N)=C(C[N+]2=CSC(CCO)=C2C)C=N1.Cl.[Cl-]

InChI

1S/C12H17N4OS.2ClH/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13;;/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15);2*1H/q+1;;/p-1

InChI key

DPJRMOMPQZCRJU-UHFFFAOYSA-M

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相关类别

应用

Thiamine hydrochloride has been used as a keratin salts medium supplement for culturing log-phase fungus. It has also been used as a supplement of VB medium the minimal medium of Vogel and Bonner.

生化/生理作用

Thiamine hydrochloride is a cheap, non-toxic and efficient catalyst for the synthesis of amidoalkyl naphthols. It inhibits the production of shikonin derivatives by suspension cultures of Lithospermum erythrorhizon. Additionally, thiamine hydrochloride addition to apple juice concentrates reduces its patulin content.
Thiamine hydrochloride is a hydrochloride salt form of thiamine (Vitamin B1). It is crucial for aerobic metabolism, cell growth, transmission of nerve impulses and acetylcholine synthesis.

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H319

危险分类

Eye Irrit. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCM9897
BCCM2433
BCCL4289
BCCK6463
BCCJ3667

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Y Fujita et al.
Plant cell reports, 1(2), 61-63 (1981-12-01)
An excellent new medium was developed for the production of shikonin derivatives by suspension cultures of Lithospermum erythrorhizon. We investigated the effects of all the components of White's medium on the production of these derivatives. Nitrate, phosphate, copper, sulfate and
Thiamine hydrochloride as an efficient catalyst for the synthesis of amidoalkyl naphthols.
Min Lei
Tetrahedron Letters, 50, 6393-6397 (2009)
Thermodynamics of (solute+ solute) and (solute+ solvent) interactions of homologous series of amino acids with thiamine hydrochloride in aqueous medium at T=(305.15, 310.15, 315.15) K: A volumetric and acoustic approach
Kumar H and Behal I
The Journal of Chemical Thermodynamics, 102, 48-62 (2016)
G Apodaca et al.
Infection and immunity, 57(10), 3081-3090 (1989-10-01)
Trichophyton rubrum is the most common dermatophyte of humans and normally colonizes the superficial layers of the epidermis (stratum corneum). Several proteinases with a possible role in the metabolism of host proteins have been purified from this fungus. The regulation
G E Degnen et al.
Journal of bacteriology, 117(2), 477-487 (1974-02-01)
A mutator gene, mutD5, whose phenotype is conditional, has been identified in Escherichia coli. By P1 transduction it has been shown to lie at about 5.7 min on the chromosome, being co-transduced with proA and argF. In rich medium, streptomycin-
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