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Merck
CN

05670

尿囊素

≥98.0% (N)

别名:

NSC 7606, 5-脲基海因, 乙醛酸二酰脲

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关于此项目

经验公式(希尔记法):
C4H6N4O3
化学文摘社编号:
分子量:
158.12
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
202-592-8
Beilstein/REAXYS Number:
102364
MDL number:
Assay:
≥98.0% (N)
Form:
powder
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InChI key

POJWUDADGALRAB-UHFFFAOYSA-N

InChI

1S/C4H6N4O3/c5-3(10)6-1-2(9)8-4(11)7-1/h1H,(H3,5,6,10)(H2,7,8,9,11)

SMILES string

NC(=O)NC1NC(=O)NC1=O

assay

≥98.0% (N)

form

powder

ign. residue

≤0.2%

mp

230 °C (dec.) (lit.)

functional group

amine

Quality Level

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Application

反应物用于:
抗菌剂用曼尼希碱的合成
抗肿瘤药舒洛芬类似物的合成

Biochem/physiol Actions

通过尿酸途径的嘌呤代谢物。尿酸也可与自由基反应生成尿囊素,因此尿囊素可作为氧化应激反应的有效生物标记。

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Khairia M. Youssef, et al
Medicinal Chemistry Research, 11, 481-503 (2003)
Sh. Joshi
Oxidation Communications, 32, 714-723 (2009)
Raymond Javan Chan et al.
Radiation oncology (London, England), 7, 121-121 (2012-08-02)
Radiation-induced skin reaction (RISR) is one of the most common and distressing side effects of radiotherapy in patients with cancer. It is featured with swelling, redness, itching, pain, breaks in skin, discomfort, and a burning sensation. There is a lack
Juan Luis Díaz-Leal et al.
Journal of experimental botany, 63(11), 4095-4106 (2012-03-24)
The ureides allantoin and allantoate are key molecules in the transport and storage of nitrogen in ureide legumes. In shoots and leaves from Phaseolus vulgaris plants using symbiotically fixed nitrogen as the sole nitrogen source, ureide levels were roughly equivalent
Adviye A Tolun et al.
Annals of epidemiology, 22(12), 892-894 (2012-10-16)
Oxidative stress has been implicated in Down syndrome (DS) pathology. This study compares DS individuals and controls on their urinary levels of allantoin and 2,3-dinor-iPF2α-III; these biomarkers have been previously validated in a clinical model of oxidative stress. Urine samples

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