InChI key
JGDITNMASUZKPW-UHFFFAOYSA-K
InChI
1S/Al.3ClH.6H2O/h;3*1H;6*1H2/q+3;;;;;;;;;/p-3
SMILES string
Cl[Al](Cl)Cl.O.O.O.O.O.O
agency
USP/NF, tested according to Ph. Eur.
vapor pressure
1 mmHg ( 100 °C)
reaction suitability
reagent type: catalyst
core: aluminum
solubility
H2O: soluble 1gm in 0.9ml, alcohol: soluble 1 gm in 4 ml, diethyl ether: soluble, glycerol: soluble, propylene glycol: soluble
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Application
Aluminum chloride hexahydrate has been used to prepare aluminum maltol and to study its toxicity in rabbits.
Biochem/physiol Actions
Aluminum chloride hexahydrate possess antimicrobial activity, when used in an aqueous form in an antiperspirant formulation. Aluminum chloride can stimulate neurofibrillary changes in neurons of spinal cord and cerebrum in the developing rabbit′s brain.
Preparation Note
1 gm of aluminum chloride hexahydrate dissolves in 0.9 ml water and 4 ml of alcohol. It is also soluble in glycerol, ether and propylene glycol.
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Skin Corr. 1B - STOT RE 1
target_organs
Lungs
supp_hazards
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
新产品
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R L Bertholf et al.
Toxicology and applied pharmacology, 98(1), 58-74 (1989-03-15)
We studied the toxicity of an intravenously injected, water-soluble aluminum complex (aluminum maltol) in 20 young adult male New Zealand white rabbits over a period of 8 to 30 weeks. Sixteen rabbits injected with aluminum-free maltol and 15 untreated rabbits
E Hölzle et al.
Archives of dermatological research, 272(3-4), 321-329 (1982-01-01)
To document deodorant efficacy the antimicrobial activity of a gelatinous antiperspirant formulation of aqueous aluminum chloride hexahydrate was investigated. In vitro assays demonstrated highly bactericidal activity on microorganisms comprising the resident axillary skin flora, including micrococcaceae and aerobic diphtheroid bacteria.
H M Wisniewski et al.
Annals of neurology, 8(5), 479-490 (1980-11-01)
Aluminum chloride injected into the brains of developing rabbits produced profound neurofibrillary changes to neurons of spinal cord and cerebrum similar to those produced in adult rabbits, along with a variety of clinical symptoms with the exception of seizures. Approximately
Dragana M Vucić et al.
Acta poloniae pharmaceutica, 70(6), 1021-1026 (2014-01-05)
Antibacterial and antioxidant activity, total phenolic and flavonoid concentrations of aqueous, ethanol and ethyl acetate extracts from the leaves and flowers of Erica herbacea L. were studied. In vitro antibacterial activity of the extracts was determined by macrodilution method. Minimum
Syed Husain Mustafa Rizvi et al.
PloS one, 9(5), e98409-e98409 (2014-06-01)
Aluminium (Al) is the third most abundant element in the earth's crust and its compounds are used in the form of house hold utensils, medicines and in antiperspirant etc. Increasing number of evidences suggest the involvement of Al+3 ions in
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