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Merck
CN

07538

Echinacoside

analytical standard

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关于此项目

经验公式(希尔记法):
C35H46O20
化学文摘社编号:
分子量:
786.73
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
4778612
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产品名称

Echinacoside, analytical standard

InChI

1S/C35H46O20/c1-14-24(42)26(44)29(47)35(51-14)55-32-30(48)34(49-9-8-16-3-6-18(38)20(40)11-16)53-22(13-50-33-28(46)27(45)25(43)21(12-36)52-33)31(32)54-23(41)7-4-15-2-5-17(37)19(39)10-15/h2-7,10-11,14,21-22,24-40,42-48H,8-9,12-13H2,1H3/b7-4+/t14-,21+,22+,24-,25+,26+,27-,28+,29+,30+,31+,32+,33+,34+,35-/m0/s1

SMILES string

C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](OCCc3ccc(O)c(O)c3)O[C@H](CO[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[C@H]2OC(=O)\C=C\c5ccc(O)c(O)c5)[C@H](O)[C@H](O)[C@H]1O

InChI key

FSBUXLDOLNLABB-ISAKITKMSA-N

grade

analytical standard

assay

≥98% (HPLC)

shelf life

limited shelf life, expiry date on the label

application(s)

food and beverages

format

neat

storage temp.

2-8°C

Quality Level

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Biochem/physiol Actions

Caffeic acid glycoside found in herbal medicine. Potential therapeutic for Parkinson′s disease.

General description

Echinacoside (ECH) is a typical phenylethanoid glycoside. It is known to contain multiple unstable chemical bonds and high reactive functional groups which aids to pathways involving degradation and metabolism. It is isolated from the stems of Cistanches salsa. It is a crude drug mostly used as antisenium and antifatigue agents.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Yuxin Wang et al.
Talanta, 80(2), 572-580 (2009-10-20)
Metabolite identification for the compounds that undergo multiple and sequential metabolism is still a great challenge. Echinacoside (ECH), a typical phenylethanoid glycoside, contains multiple unstable chemical bonds and high reactive functional groups which are susceptible to multiple pathways of degradation
Hao Yang et al.
Biomedical chromatography : BMC, 23(6), 630-637 (2009-03-12)
A rapid and sensitive method based on liquid chromatography/tandem mass spectrometry (LC/MS/MS) for the determination of echinacoside in rat plasma was established and fully validated. A single step of liquid-liquid extraction with n-butanol was utilized. Chromatographic separation of the analyte
Rong Kuang et al.
Planta medica, 75(14), 1499-1504 (2009-06-24)
We have investigated the protective effects of echinacoside (ECH), one of the phenylethanoid glycosides, on H(2)O(2)-induced cytotoxicity in the rat pheochromocytoma cell line (PC12 cells). Our data show that application of ECH to H(2)O(2)-injured PC12 cells (HIPCs) increased cell viability
Parida Yamada et al.
Planta medica, 76(14), 1512-1518 (2010-04-01)
The immediate-type allergic reaction is involved in many allergic diseases such as asthma, allergic rhinitis, and sinusitis. In this study, we investigated the effect of acteoside extracted from CISTANCHE TUBULOSA (Schrenk) R. Wight on the basophilic cell-mediated allergic reaction. The
Cunqin Jia et al.
Drug metabolism and disposition: the biological fate of chemicals, 37(2), 431-438 (2008-11-22)
Echinacoside (ECH) is one of the major active phenylethanoid glycosides (PEGs) in famous traditional Chinese medicine, Herba Cistanches. Although it has various bioactivities, such as antioxidation, neuroprotection, and hepatoprotection, knowledge about its metabolic fate is scant. In the present study

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