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07604

2-巯基乙醇

别名:

2-巯基乙醇, β-巯基乙醇, 2-羟乙基硫醇, BME, 硫代二甘醇

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关于此项目

线性分子式:
HSCH2CH2OH
化学文摘社编号:
60-24-2
分子量:
78.13
EC Number:
200-464-6
UNSPSC Code:
12161504
NACRES:
NA.21
Beilstein/REAXYS Number:
773648
MDL number:
MFCD00004890
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biological source

synthetic

Quality Level

400

vapor density

2.69 (vs air)

vapor pressure

1 mmHg ( 20 °C)

assay

≥99.0% (GC), 99.0-101.0% (iodometric, RT)

form

liquid

expl. lim.

18 %

concentration

14.3 M (pure liquid)

refractive index

n20/D 1.500 (lit.)

bp

157 °C (lit.)

solubility

H2O: 1 mL/mL, clear, colorless

density

1.114 g/mL at 25 °C (lit.)

cation traces

Cu: ≤1 mg/kg, Fe: ≤1 mg/kg, Ni: ≤1 mg/kg, Pb: ≤5 mg/kg, Zn: ≤1 mg/kg

storage temp.

2-8°C

SMILES string

OCCS

InChI

1S/C2H6OS/c3-1-2-4/h3-4H,1-2H2

InChI key

DGVVWUTYPXICAM-UHFFFAOYSA-N

Application

BME 适用于在聚丙烯酰胺凝胶电泳前还原蛋白质二硫键，通常用于 SDS-PAGE 的样品缓冲液，浓度为 5%。切割分子间（亚基之间）二硫键允许蛋白质的亚基在 SDS-PAGE 上独立分离。切割分子内（亚基内）二硫键可使亚基完全变性，从而使每个肽根据其链长迁移，而不受二级结构的影响。

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Danger

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1A - STOT RE 2 Oral

target_organs

Liver,Heart

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

165.2 °F - closed cup

flash_point_c

74 °C - closed cup

法规信息

危险化学品

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCF5677
BCBP7089V
BCBP7091V
BCBP7090V

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Chao Wan et al.
Science advances, 6(13), eaay9789-eaay9789 (2020-04-02)
Radiotherapy (RT) is routinely used in cancer treatment, but expansion of its clinical indications remains challenging. The mechanism underlying the radiation-induced bystander effect (RIBE) is not understood and not therapeutically exploited. We suggest that the RIBE is predominantly mediated by
Hong Peng et al.
Autophagy, 16(4), 698-708 (2019-06-27)
SQSTM1/p62 (sequestosome 1) is a critical macroautophagy/autophagy receptor that promotes the formation and degradation of ubiquitinated aggregates. SQSTM1 can be modified by ubiquitination, and this modification modulates its autophagic activity. However, the molecular mechanisms underpinning its reversible deubiquitination have never

全球贸易项目编号

货号GTIN
259640-5G04061826075395
07604-100ML04061838069016
07604-1L04061838110268