07748
加巴喷丁
pharmaceutical secondary standard; traceable to USP
别名:
1-（氨甲基）-环己烷乙酸, 加巴喷丁
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经验公式（希尔记法）:
C9H17NO2
化学文摘社编号:
分子量:
171.24
EC Number:
262-076-3
UNSPSC Code:
41116000
MDL number:
Beilstein/REAXYS Number:
2359739
InChI key
UGJMXCAKCUNAIE-UHFFFAOYSA-N
InChI
1S/C9H17NO2/c10-7-9(6-8(11)12)4-2-1-3-5-9/h1-7,10H2,(H,11,12)
SMILES string
NCC1(CC(O)=O)CCCCC1
agency
traceable to USP 1287303
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Barbara J Mason et al.
JAMA internal medicine, 174(1), 70-77 (2013-11-06)
Approved medications for alcohol dependence are prescribed for less than 9% of US alcoholics. To determine if gabapentin, a widely prescribed generic calcium channel/γ-aminobutyric acid-modulating medication, increases rates of sustained abstinence and no heavy drinking and decreases alcohol-related insomnia, dysphoria
Y Yu et al.
Clinical pharmacology and therapeutics, 94(4), 519-524 (2013-05-28)
To investigate the so-called "drift" with generic-generic drug substitution, a single-dose, four-way crossover comparative bioavailability study was performed involving 24 healthy subjects and three generic and one branded formulation of a tablet containing 800 mg gabapentin as test medication. The results
Adam Bisaga et al.
Drug and alcohol dependence, 81(3), 267-274 (2005-09-20)
In laboratory animals, augmentation of GABA neurotransmission results in inhibition of cocaine self-administration and inhibition of reinstatement to cocaine-seeking behaviors. If parallel effects were observed in humans, GABA-ergic medication should be effective both in the abstinence-induction as well as in
Carlos C Câmara et al.
Neuroscience letters, 556, 93-98 (2013-10-22)
Gabapentin (GBP) is an anti-convulsive drug often used as analgesic to control neuropathic pain. This study aimed at evaluating whether oral GBP treatment could improve nerve inflammation response after sciatic nerve constriction in association with selected pain and motor spontaneous
Richard Rauck et al.
Anesthesiology, 119(3), 675-686 (2013-07-10)
Oral gabapentin is approved as an anticonvulsant medication and to treat postherpetic neuralgia. Its nonopioid properties and presumed spinal site of analgesic action made the study on intrathecal gabapentin attractive to establish the minimum effective dose for a later, pivotal
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