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10680

邻氨基苯甲酸

Name: 邻氨基苯甲酸
Brand: SIAL

≥99.5% (T), solid, puriss. p.a.

别名:

2-AA, 2-氨基苯甲酸

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关于此项目

线性分子式:

2-(H₂N)C₆H₄CO₂H

化学文摘社编号:

118-92-3

分子量:

137.14

NACRES:

NA.21

PubChem Substance ID:

57646812

UNSPSC Code:

12352100

EC Number:

204-287-5

MDL number:

MFCD00007712

Beilstein/REAXYS Number:

471803

Assay:

≥99.5% (T)

Form:

solid

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属性

产品名称

邻氨基苯甲酸, puriss. p.a., ≥99.5% (T)

vapor density

4.7 (vs air)

Quality Level

200

grade

puriss. p.a.

assay

≥99.5% (T)

form

solid

ign. residue

≤0.05% (as SO₄)

mp

144-148 °C (lit.), 145-147 °C

anion traces

chloride (Cl^-): ≤500 mg/kg, sulfate (SO₄^2-): ≤100 mg/kg

cation traces

Ca: ≤100 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤50 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Na: ≤50 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg

functional group

carboxylic acid

SMILES string

Nc1ccccc1C(O)=O

InChI

1S/C7H7NO2/c8-6-4-2-1-3-5(6)7(9)10/h1-4H,8H2,(H,9,10)

InChI key

RWZYAGGXGHYGMB-UHFFFAOYSA-N

说明

General description

Anthranilic acid is an ortho-substituted aniline derivative. Anthranilic acid can be obtained from carbozole via microbial transformation using Pseudomonas stutzeri. It is a substrate of enzyme anthranilate hydroxylase found in Aspergillus niger.

Application

Anthranilic acid (AA) may be employed for the following studies:

Fluorescent labeling of glycans.
Synthesis of triptycene and derivatives, via diazotization reaction.
As fluorescent label for the facile labeling of oligosaccharides (acidic and neutral).
As fluorescent label for carbohydrate analysis.
Derivatization of oligosaccharides.
Preparation of poly(aniline-co-o-anthranilic acid) copolymers.

Anthranilic acid has been used in the microwave-assisted preparation of 2-heptyl-3-hydroxy-4(1H)-quinolone, also called as Pseudomonas quinolone signal, which finds applications in quorum sensing mechanism.

用于非选择性、高效的糖基荧光标记。

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pictograms

GHS05

signalword

Danger

hcodes

H318

pcodes

P280 - P305 + P351 + P338

Hazard Classifications

Eye Dam. 1

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

302.0 °F - closed cup

flash_point_c

150 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

法规信息

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分析证书(COA)

Lot/Batch Number

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实验方案

Mass Spectrometry of Glycans

Explore mass spectrometry analysis of glycans for glycomic & glycoproteomic neutral & acidic glycan analysis. See a general mass spec glycan analysis procedure.

聚糖的质谱

该聚糖质谱分析方案，被称之为干液滴法，基于原始的MALDI实验并依然是MS领域中最常用的方法。

"Microbial transformation of carbazole to anthranilic acid by Pseudomonas stutzeri"

Hisatsuka K and Sato M

Bioscience, Biotechnology, and Biochemistry, 58(01), 213-214 (1994)

Water-Soluble Poly (aniline-co-o-anthranilic acid) Copolymers.

Nguyen MT and Diaz AF.

Macromolecules, 28(9), 3411-3415 (1995)

High resolution and high sensitivity methods for oligosaccharide mapping and characterization by normal phase high performance liquid chromatography following derivatization with highly fluorescent anthranilic acid.

K R Anumula et al.

Glycobiology, 8(7), 685-694 (1998-06-11)

Facile labeling of oligosaccharides (acidic and neutral) in a nonselective manner was achieved with highly fluorescent anthranilic acid (AA, 2-aminobenzoic acid) (more than twice the intensity of 2-aminobenzamide, AB) for specific detection at very high sensitivity. Quantitative labeling in acetate-borate

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282715-5G	04061833014011
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10680-25G	04061838674401