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Merck
CN

10784

安替吡啉

tested according to Ph. Eur.

别名:

安替比林, 2,3-二甲基-1-苯基-3-吡唑啉-5-酮, 非那宗

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关于此项目

经验公式(希尔记法):
C11H12N2O
化学文摘社编号:
分子量:
188.23
UNSPSC Code:
41116107
NACRES:
NA.21
PubChem Substance ID:
EC Number:
200-486-6
Beilstein/REAXYS Number:
157775
MDL number:
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Quality Level

agency

USP/NF, tested according to Ph. Eur.

form

crystals and lumps, powder

mp

109-111 °C (lit.)

solubility

H2O: soluble 1 gm in less than 1ml, alcohol: soluble 1 gm in 1.3 ml, chloroform: soluble 1 gm in 1 ml, diethyl ether: soluble 1 gm in 43 ml

application(s)

pharmaceutical (small molecule)

SMILES string

CN1N(C(=O)C=C1C)c2ccccc2

InChI

1S/C11H12N2O/c1-9-8-11(14)13(12(9)2)10-6-4-3-5-7-10/h3-8H,1-2H3

InChI key

VEQOALNAAJBPNY-UHFFFAOYSA-N

Gene Information

human ... PTGS1(5742)

Application

安替比林已用于免疫印迹。它还被用作内部参考标记,用于研究含铂药物顺铂在体外在人胎盘中的转运特性。

Biochem/physiol Actions

安替比林也称为非那松或非那松,是一种具有镇痛、解热和血小板抑制作用的抗炎剂。


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pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 1

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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E Girbal-Neuhauser et al.
Journal of immunology (Baltimore, Md. : 1950), 162(1), 585-594 (1999-01-14)
Antifilaggrin autoantibodies (AFA) are a population of IgG autoantibodies associated to rheumatoid arthritis (RA), which includes the so-called "antikeratin" Abs and antiperinuclear factor. AFA are the most specific serological markers of RA. We previously showed that they recognize human epidermal
Eyad Al-Saleh et al.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 21(10), 726-731 (2008-11-18)
Platinum-containing drugs are used extensively in the treatment of various malignancies in humans. Data are scarce on the maternal-fetal transport characteristics in humans of one such widely used drug, cisplatin, and this prompted us to study its transport characteristics in
Gro Klitgaard Povlsen et al.
BMC neuroscience, 14, 34-34 (2013-03-19)
Upregulation of vasoconstrictor receptors in cerebral arteries, including endothelin B (ETB) and 5-hydroxytryptamine 1B (5-HT(1B)) receptors, has been suggested to contribute to delayed cerebral ischemia, a feared complication after subarachnoid hemorrhage (SAH). This receptor upregulation has been shown to be



全球贸易项目编号

货号GTIN
10784-100G04061838675828