10784
安替吡啉
tested according to Ph. Eur.
别名:
安替比林, 2,3-二甲基-1-苯基-3-吡唑啉-5-酮, 非那宗
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关于此项目
经验公式（希尔记法）:
C11H12N2O
化学文摘社编号:
分子量:
188.23
UNSPSC Code:
41116107
NACRES:
NA.21
PubChem Substance ID:
EC Number:
200-486-6
Beilstein/REAXYS Number:
157775
MDL number:
产品名称
安替吡啉, tested according to Ph. Eur.
InChI key
VEQOALNAAJBPNY-UHFFFAOYSA-N
InChI
1S/C11H12N2O/c1-9-8-11(14)13(12(9)2)10-6-4-3-5-7-10/h3-8H,1-2H3
SMILES string
CN1N(C(=O)C=C1C)c2ccccc2
agency
USP/NF
tested according to Ph. Eur.
form
crystals and lumps
powder
mp
109-111 °C (lit.)
solubility
H2O: soluble 1 gm in less than 1ml
alcohol: soluble 1 gm in 1.3 ml
chloroform: soluble 1 gm in 1 ml
diethyl ether: soluble 1 gm in 43 ml
application(s)
pharmaceutical (small molecule)
Quality Level
Gene Information
human ... PTGS1(5742)
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Application
安替比林已用于免疫印迹。它还被用作内部参考标记，用于研究含铂药物顺铂在体外在人胎盘中的转运特性。
Biochem/physiol Actions
安替比林也称为非那松或非那松，是一种具有镇痛、解热和血小板抑制作用的抗炎剂。
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 1
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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Platinum-containing drugs are used extensively in the treatment of various malignancies in humans. Data are scarce on the maternal-fetal transport characteristics in humans of one such widely used drug, cisplatin, and this prompted us to study its transport characteristics in
E Girbal-Neuhauser et al.
Journal of immunology (Baltimore, Md. : 1950), 162(1), 585-594 (1999-01-14)
Antifilaggrin autoantibodies (AFA) are a population of IgG autoantibodies associated to rheumatoid arthritis (RA), which includes the so-called "antikeratin" Abs and antiperinuclear factor. AFA are the most specific serological markers of RA. We previously showed that they recognize human epidermal
Gro Klitgaard Povlsen et al.
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Upregulation of vasoconstrictor receptors in cerebral arteries, including endothelin B (ETB) and 5-hydroxytryptamine 1B (5-HT(1B)) receptors, has been suggested to contribute to delayed cerebral ischemia, a feared complication after subarachnoid hemorrhage (SAH). This receptor upregulation has been shown to be
Giorgio Rizzi et al.
Cell reports, 34(11), 108867-108867 (2021-03-18)
The firing activity of dorso-medial-striatal-cholinergic interneurons (dmCINs) is a neural correlate of classical conditioning. Tonically active, they pause in response to salient stimuli, mediating acquisition of predictive cues/outcome associations. Cortical and thalamic inputs are typical of the rather limited knowledge
Factors influencing antipyrine elimination.
I H Stevenson
British journal of clinical pharmacology, 4(3), 261-265 (1977-06-01)
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