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Merck
CN

10784

Sigma-Aldrich

安替比林

tested according to Ph. Eur.

别名:

安替比林, 2,3-二甲基-1-苯基-3-吡唑啉-5-酮, 非那宗

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About This Item

经验公式(希尔记法):
C11H12N2O
CAS号:
分子量:
188.23
Beilstein:
157775
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.21

Agency

USP/NF
tested according to Ph. Eur.

质量水平

形式

crystals and lumps
powder

mp

109-111 °C (lit.)

溶解性

H2O: soluble 1 gm in less than 1ml
alcohol: soluble 1 gm in 1.3 ml
chloroform: soluble 1 gm in 1 ml
diethyl ether: soluble 1 gm in 43 ml

应用

pharmaceutical (small molecule)

SMILES字符串

CN1N(C(=O)C=C1C)c2ccccc2

InChI

1S/C11H12N2O/c1-9-8-11(14)13(12(9)2)10-6-4-3-5-7-10/h3-8H,1-2H3

InChI key

VEQOALNAAJBPNY-UHFFFAOYSA-N

基因信息

human ... PTGS1(5742)

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应用

安替比林已用于免疫印迹。它还被用作内部参考标记,用于研究含铂药物顺铂在体外在人胎盘中的转运特性。

生化/生理作用

安替比林也称为非那松或非那松,是一种具有镇痛、解热和血小板抑制作用的抗炎剂。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 1

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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Lot/Batch Number

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Eyad Al-Saleh et al.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 21(10), 726-731 (2008-11-18)
Platinum-containing drugs are used extensively in the treatment of various malignancies in humans. Data are scarce on the maternal-fetal transport characteristics in humans of one such widely used drug, cisplatin, and this prompted us to study its transport characteristics in
E Girbal-Neuhauser et al.
Journal of immunology (Baltimore, Md. : 1950), 162(1), 585-594 (1999-01-14)
Antifilaggrin autoantibodies (AFA) are a population of IgG autoantibodies associated to rheumatoid arthritis (RA), which includes the so-called "antikeratin" Abs and antiperinuclear factor. AFA are the most specific serological markers of RA. We previously showed that they recognize human epidermal
Gro Klitgaard Povlsen et al.
BMC neuroscience, 14, 34-34 (2013-03-19)
Upregulation of vasoconstrictor receptors in cerebral arteries, including endothelin B (ETB) and 5-hydroxytryptamine 1B (5-HT(1B)) receptors, has been suggested to contribute to delayed cerebral ischemia, a feared complication after subarachnoid hemorrhage (SAH). This receptor upregulation has been shown to be
Factors influencing antipyrine elimination.
I H Stevenson
British journal of clinical pharmacology, 4(3), 261-265 (1977-06-01)
Antipyrine as a model drug to study hepatic drug-metabolizing capacity.
H E Poulsen et al.
Journal of hepatology, 6(3), 374-382 (1988-06-01)

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