131105
原黄素 盐酸盐
Dye content 95 %
别名:
Proflavine hydrochloride, Proflavine monohydrochloride
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关于此项目
经验公式（希尔记法）:
C13H11N3 · HCl
化学文摘社编号:
分子量:
245.71
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
EC Number:
213-459-9
MDL number:
产品名称
原黄素 盐酸盐, Dye content 95 %
InChI key
PBBGTVBGXBUVLT-UHFFFAOYSA-N
InChI
1S/C13H11N3.ClH/c14-10-3-1-8-5-9-2-4-11(15)7-13(9)16-12(8)6-10;/h1-7H,14-15H2;1H
SMILES string
Cl[H].Nc1ccc2cc3ccc(N)cc3nc2c1
assay
94.0% (HPLC)
form
powder
composition
Dye content, 95%
mp
270 °C (dec.) (lit.)
solubility
H2O: 1 mg/mL, clear
λmax
456 nm
ε (extinction coefficient)
50000 at 260 nm in methanol
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
Application
3, 6-Diaminoacridine hydrochloride has been used for studying cation transfer at the liquid–liquid interface.
An intercalating dye.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Anirban Basu et al.
Journal of biomolecular structure & dynamics, 38(6), 1590-1597 (2019-05-07)
The binding of proflavine, an acriflavine derivative, with the RNA polynucletodide polyadenylic acid-polyuridylic acid is investigated here to understand the structural and thermodynamic basis of the binding process. Such binding data are crucial for designing viable theraperutic agents. Spectroscopic studies
Anirban Basu et al.
Journal of photochemistry and photobiology. B, Biology, 165, 42-50 (2016-10-22)
Interaction of proflavine with hemoglobin (Hgb) was studied employing spectroscopy, calorimetry, and atomic force microscopy. The equilibrium constant was found to be of the order 10
Anna Porfireva et al.
Nanomaterials (Basel, Switzerland), 10(5) (2020-05-14)
A DNA sensor has been developed for the determination of doxorubicin by consecutive electropolymerization of an equimolar mixture of Azure B and proflavine and adsorption of native DNA from salmon sperm on a polymer film. Electrochemical investigation showed a difference
Miklós Nagy et al.
Scientific reports, 9(1), 8250-8250 (2019-06-05)
Amino-isocyanoacridines (ICAAcs), as first members of their class, turned out to be a novel, multifunctional acridine orange (AO) type dye family with a number of additional favorable properties. They have enhanced solvatochromic emission range, low quantum yields (ΦF = 2.9-0.4%) in water
Membrane activity of ionisable drugs ? a task for liquid?liquid electrochemistry?
Malkia A
Electrochemical Communications, 5:6, 473-479 (2003)
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