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Merck
CN

14510

1,2-双(2-氨基苯氧基)乙烷- N,N,N′,N′-四乙酸

≥96.0% (HPLC)

别名:

BAPTA, 亚乙二氧基双(邻亚苯基次氮基)四乙酸

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关于此项目

经验公式(希尔记法):
C22H24N2O10
化学文摘社编号:
分子量:
476.43
UNSPSC Code:
12352112
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
5192406
Assay:
≥96.0% (HPLC)
Form:
powder
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Quality Level

assay

≥96.0% (HPLC)

form

powder

fluorescence

λex 251 nm; λem 363 nm, λex 274 nm; λem 363 nm (With Calcium)

functional group

amine, carboxylic acid

storage temp.

2-8°C

SMILES string

OC(=O)CN(CC(O)=O)c1ccccc1OCCOc2ccccc2N(CC(O)=O)CC(O)=O

InChI

1S/C22H24N2O10/c25-19(26)11-23(12-20(27)28)15-5-1-3-7-17(15)33-9-10-34-18-8-4-2-6-16(18)24(13-21(29)30)14-22(31)32/h1-8H,9-14H2,(H,25,26)(H,27,28)(H,29,30)(H,31,32)

InChI key

FTEDXVNDVHYDQW-UHFFFAOYSA-N

General description

1,2-双(2-氨基苯氧基)乙烷-N,N,N′,N′-四乙酸是一种高选择性的钙螯合剂。研究了载钙 1,2-双(2-氨基苯氧基)乙烷-N,N,N′,N′-四乙酸 (CaBAPTA) 在紫花牡蛎体毛中对羧基荧光素细胞间扩散的影响。为 1,2-双(2-氨基苯氧基)乙烷-N,N,N,N′,N′-四乙酸四(乙酰氧甲酯)(BAPTA-AM) 在大鼠尿液中的代谢产物。
pH 8.0。高选择性钙螯合剂。适合光谱法监测Ca2+浓度

Application

1,2-双(2-氨基苯氧基)乙烷-N,N,N′,N′′-四乙酸分光光度法测定 ca2+水平。甲氧滴滴涕可作为胞浆 Ca²+ 的螯合剂,用于研究甲氧滴滴涕对 HA59T 人肝癌细胞胞浆游离 Ca²+ 浓度及细胞凋亡的影响。
高选择性钙螯合试剂。适用于分光光度法监测 Ca2+ 水平


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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Chi-Ting Horng et al.
The Chinese journal of physiology, 58(1), 1-8 (2015-02-18)
Methoxychlor, an organochlorine pesticide, is thought to be an endocrine disrupter that affects Ca²⁺ homeostasis and cell viability in different cell models. This study explored the action of methoxychlor on cytosolic free Ca²⁺ concentrations ([Ca²⁺]i) and apoptosis in HA59T human
E B Tucker
Planta, 182(1), 34-38 (1990-08-01)
The effect of microinjected calcium-loaded 1,2-bis(2-aminophenoxy) ethane-N,N,N',N'-tetraacetic acid (CaBAPTA) on cell-to-cell diffusion of carboxyfluorescein (CF) was examined in staminal hairs of S. purpurea Boom. The CaBAPTA was microinjected into the cytoplasm of the staminal hairs either with CF or prior
Mayeul Collot et al.
Journal of the American Chemical Society, 134(36), 14923-14931 (2012-07-24)
We designed Calcium Rubies, a family of functionalizable BAPTA-based red-fluorescent calcium (Ca(2+)) indicators as new tools for biological Ca(2+) imaging. The specificity of this Ca(2+)-indicator family is its side arm, attached on the ethylene glycol bridge that allows coupling the



全球贸易项目编号

货号GTIN
14510-1G-F04061826661468
14510-100MG-F04061833489802
14510-250MG-F04061833489819
14510-50G-F04061838736116