Merck
CN

15527

Sigma-Aldrich

甘氨酸

meets analytical specification of Ph. Eur., BP, USP, 99-101% (based on anhydrous substance)

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别名:
氨基乙酸, 甘氨酸
线性分子式:
NH2CH2COOH
CAS号:
分子量:
75.07
Beilstein:
635782
EC 号:
MDL编号:
eCl@ss:
32160406
PubChem化学物质编号:
NACRES:
NA.21

质量水平

检测方案

99-101% (based on anhydrous substance)

形式

crystalline powder

质量

meets analytical specification of Ph. Eur., BP, USP

technique(s)

IR spectroscopy: suitable

杂质

hydrolyzable substances, complies
organic volatile impurities, complies (GC)
residual solvents, complies
≤0.001% heavy metals (as Pb)
≤1.0% ninhydrin-positive substances

灼烧残渣

≤0.1% (as SO4)

缺失

≤0.2% loss on drying, 105 °C, 2 h

颜色

white

pH值(酸碱度)

5.9-6.4 (20 °C, 5%)

pKa (25 °C)

(1) 2.35, (2) 9.60
2.35

mp

240 °C (dec.) (lit.)

溶解性

H2O: soluble 25 gm in 100 ml at 25 degrees c
H2O: soluble 39.1 gm in 100 ml at 50 degrees c
alcohol: soluble 0.06 gm in 100 gm (Absolute)
pyridine: soluble 164 parts
alcohol: very slightly soluble
diethyl ether: very slightly soluble

痕量阴离子

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤50 mg/kg

适用性

complies for appearance of solution
complies for reaction against H2SO4
in accordance for identity (IR)

SMILES string

NCC(O)=O

InChI

1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

InChI key

DHMQDGOQFOQNFH-UHFFFAOYSA-N

Gene Information

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相关类别

应用

使用甘氨酸制备全血样本中的血小板,并研究白细胞中细胞因子表达的刺激。用于生化和耐受性试验。

生化/生理作用

甘氨酸通过激活中枢神经系统,在降低糖尿病和肥胖患者的血脂水平中发挥关键作用。脑缺氧时,甘氨酸能稳定脑线粒体的能量紊乱。当与葡萄糖一起使用时,它也增加了猪囊胚的体外发育。
脊髓中的抑制性神经递质,NMDA受体的变构调节器。

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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Jessica T Y Yue et al.
Circulation research, 110(10), 1345-1354 (2012-04-05)
Dysregulation of hepatic triglyceride (TG)-rich very low-density lipoproteins (VLDL-TG) in obesity and type 2 diabetes contributes to the dyslipidemia that leads to cardiovascular morbidity. The central nervous system (CNS), particularly the hypothalamus, regulates hepatic lipid metabolism. Although the underlying neurocircuitry
Tomomi Mito et al.
Reproduction, fertility, and development, 24(3), 443-450 (2012-03-10)
In the present study, the effects of glucose and/or glycine on the in vitro development of Day 5 (Day 0=IVF) porcine blastocysts were determined. The addition of 2.5-10 mM glucose to the chemically defined culture medium porcine zygote medium (PZM)-5
A A Selin et al.
Bulletin of experimental biology and medicine, 153(1), 44-47 (2012-07-19)
Glycine stabilizes energetics of brain mitochondria under conditions of brain hypoxia in vivo modeled by ligation of the common carotid artery in rats. Hypoxia reduced respiratory control in brain cortex mitochondria from 7.7 ± 0.5 to 4.5 ± 0.3. Preliminary
F J Neumann et al.
Circulation, 95(10), 2387-2394 (1997-05-20)
Activated platelets tether and activate myeloid leukocytes. To investigate the potential relevance of this mechanism in acute myocardial infarction (AMI), we examined cytokine induction by leukocyte-platelet adhesion and the occurrence of leukocyte-platelet conjugates in patients with AMI. We obtained peripheral
F Megraud et al.
Journal of clinical microbiology, 22(6), 1007-1010 (1985-12-01)
"Campylobacter pyloridis" has been recently described as a gastritis-associated bacterium. We studied 20 strains. The bacteria had most of the characteristics of Campylobacter spp. strains. They were hippurate negative and tolerant to triphenyl tetrazolium chloride (at 0.4 and 1 mg/ml).

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