16682
(R)-泛酸 钠盐
≥95% (GC)
别名:
(2R)-2,4-二羟基-3,3-二甲基丁酸 单钠盐, (R)-2,4-二羟基-3,3-二甲基丁酸 钠盐, 钠 (R)-泛酸, 钠D-泛酸
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关于此项目
经验公式（希尔记法）:
C6H11NaO4
化学文摘社编号:
分子量:
170.14
MDL number:
UNSPSC Code:
12352106
NACRES:
NA.25
Beilstein/REAXYS Number:
6119584
SMILES string
[Na+].[O-]C(=O)[C@H](O)C(CO)(C)C
InChI
1S/C6H12O4.Na/c1-6(2,3-7)4(8)5(9)10;/h4,7-8H,3H2,1-2H3,(H,9,10);/q;+1/p-1/t4-;/m0./s1
InChI key
XTIMSSMEPPKSQD-WCCKRBBISA-M
assay
≥95% (GC)
optical activity
[α]/D 8.0±1.0°, c = 1 in H2O
storage temp.
−20°C
Quality Level
相关类别
Biochem/physiol Actions
(R)-泛解酸是磷酸泛酸生物合成途径中的中间体，在植物和微生物中用于由缬氨酸从头合成R-泛酸（维生素B5）。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
13C-NMR and 1H-1H NOEs of Coenzyme A: conformation of the pantoic acid moiety.
Dordine, R.L., et al.
Bioorganic Chemistry, 23, 169-181 (1995)
Hiroya Tomita et al.
Journal of bacteriology, 194(19), 5434-5443 (2012-08-07)
Although bacteria and eukaryotes share a pathway for coenzyme A (CoA) biosynthesis, we previously clarified that most archaea utilize a distinct pathway for the conversion of pantoate to 4'-phosphopantothenate. Whereas bacteria/eukaryotes use pantothenate synthetase and pantothenate kinase (PanK), the hyperthermophilic
Analysis of stereochemistry of enzymically formed pantoyl lactone or pantoic acid by gas chromatography and circular dichroism.
D R Wilken et al.
Analytical biochemistry, 112(1), 9-16 (1981-03-15)
Dayong Si et al.
Applied microbiology and biotechnology, 93(4), 1619-1625 (2011-11-16)
Ketopantoic acid (KPA) reductase catalyzes the stereospecific reduction of ketopantoic acid to D-pantoic acid. Based on the N-terminal amino acid sequence of KPA reductase from Stenotrophomonas maltophilia 845, the KPA reductase gene was cloned from S. maltophilia NBRC14161 and sequenced.
Michael Rothmann et al.
Journal of the American Chemical Society, 135(16), 5962-5965 (2013-04-05)
Pantetheine and its corresponding disulfide pantethine play a key role in metabolism as building blocks of coenzyme A (CoA), an essential cofactor utilized in ~4% of primary metabolism and central to fatty acid, polyketide, and nonribosomal peptide synthases. Using a
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