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经验公式(希尔记法):
C6H11NaO4
化学文摘社编号:
分子量:
170.14
MDL number:
UNSPSC Code:
12352106
NACRES:
NA.25
Beilstein/REAXYS Number:
6119584
SMILES string
[Na+].[O-]C(=O)[C@H](O)C(CO)(C)C
InChI
1S/C6H12O4.Na/c1-6(2,3-7)4(8)5(9)10;/h4,7-8H,3H2,1-2H3,(H,9,10);/q;+1/p-1/t4-;/m0./s1
InChI key
XTIMSSMEPPKSQD-WCCKRBBISA-M
assay
≥95% (GC)
optical activity
[α]/D 8.0±1.0°, c = 1 in H2O
storage temp.
−20°C
Quality Level
相关类别
Biochem/physiol Actions
(R)-泛解酸是磷酸泛酸生物合成途径中的中间体,在植物和微生物中用于由缬氨酸从头合成R-泛酸(维生素B5)。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Hiroya Tomita et al.
Journal of bacteriology, 194(19), 5434-5443 (2012-08-07)
Although bacteria and eukaryotes share a pathway for coenzyme A (CoA) biosynthesis, we previously clarified that most archaea utilize a distinct pathway for the conversion of pantoate to 4'-phosphopantothenate. Whereas bacteria/eukaryotes use pantothenate synthetase and pantothenate kinase (PanK), the hyperthermophilic
13C-NMR and 1H-1H NOEs of Coenzyme A: conformation of the pantoic acid moiety.
Dordine, R.L., et al.
Bioorganic Chemistry, 23, 169-181 (1995)
Michael Rothmann et al.
Journal of the American Chemical Society, 135(16), 5962-5965 (2013-04-05)
Pantetheine and its corresponding disulfide pantethine play a key role in metabolism as building blocks of coenzyme A (CoA), an essential cofactor utilized in ~4% of primary metabolism and central to fatty acid, polyketide, and nonribosomal peptide synthases. Using a
Analysis of stereochemistry of enzymically formed pantoyl lactone or pantoic acid by gas chromatography and circular dichroism.
D R Wilken et al.
Analytical biochemistry, 112(1), 9-16 (1981-03-15)
Dayong Si et al.
Applied microbiology and biotechnology, 93(4), 1619-1625 (2011-11-16)
Ketopantoic acid (KPA) reductase catalyzes the stereospecific reduction of ketopantoic acid to D-pantoic acid. Based on the N-terminal amino acid sequence of KPA reductase from Stenotrophomonas maltophilia 845, the KPA reductase gene was cloned from S. maltophilia NBRC14161 and sequenced.
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