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关于此项目
经验公式(希尔记法):
C9H12BNO4
化学文摘社编号:
分子量:
209.01
UNSPSC Code:
12352209
NACRES:
NA.21
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
4458616
Quality Level
assay
≥95.0% (HPLC)
storage temp.
2-8°C
SMILES string
N[C@@H](Cc1ccc(cc1)B(O)O)C(O)=O
InChI
1S/C9H12BNO4/c11-8(9(12)13)5-6-1-3-7(4-2-6)10(14)15/h1-4,8,14-15H,5,11H2,(H,12,13)/t8-/m0/s1
InChI key
NFIVJOSXJDORSP-QMMMGPOBSA-N
Application
4-二羟硼基-L-苯基丙氨酸可用作固相多肽合成的砌块。它还可用于通过钯作为催化剂进行Suzuki交叉偶联反应来合成取代三嗪衍生物作为潜在色氨酸羟化酶抑制剂。
Other Notes
酪氨酸类似物;用于通过硼中子俘获疗法治疗黑色素瘤细胞
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Maria Alejandra Dagrosa et al.
International journal of radiation oncology, biology, physics, 79(1), 262-268 (2010-10-12)
DNA lesions produced by boron neutron capture therapy (BNCT) and those produced by gamma radiation in a colon carcinoma cell line were analyzed. We have also derived the relative biologic effectiveness factor (RBE) of the neutron beam of the RA-3-
Andrea Monti Hughes et al.
Oral oncology, 47(11), 1017-1022 (2011-08-16)
Given the clinical relevance of locoregional recurrences in head and neck cancer, we developed a novel experimental model of premalignant tissue in the hamster cheek pouch for long-term studies and demonstrated the partial inhibitory effect of a single application of
Yuko Kinashi et al.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 163, 109204-109204 (2020-06-21)
Temozolomide (TMZ) is a DNA-alkylating agent used for chemo-radiotherapy of glioblastoma, which is also a target cancer for boron neutron capture therapy (BNCT). Although the DNA-repair enzyme O6-methylguanine DNA methyltransferase (MGMT) and the tumor suppressor p53 are mutated in some
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 17755-250MG | 04061838753274 |
