17929
O-Methyl-O′-succinylpolyethylene glycol 5′000
别名:
Polyethylene glycol, O-(Succinyl)-O′-methylpolyethylene glycol 5′000, Polyethylene glycol 5000 monomethyl ether succinate
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关于此项目
线性分子式:
CH3O(CH2CH2O)nCOCH2CH2COOH
化学文摘社编号:
UNSPSC Code:
51171641
NACRES:
NA.26
MDL number:
Application
Soluble polymer for solid phase synthesis of imines and β-lactams; attaching peptides to PEG
Polyethylene glycol 5000 is used in the construction of biomaterials such as biopolymers, micelles and nanostructures.
Biochem/physiol Actions
O-Methyl-O′-succinylpolyethylene glycol 5′000 is a modified monomethoxypolyethylene glycol (mPEG) wherein the hydroxyl groups are succinylated by succinic anhydride. This succinylated mPEG can then be used to synthesize tolerogenic mPEG conjugates of peptides. Tolerogenic peptide conjugates are very effective reagents for obtaining epitope-specific immunosuppression of antibody responses to immunopathogenic sites on multideterminant complex protein antigens.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves