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经验公式(希尔记法):
C6H6N4O4
化学文摘社编号:
分子量:
198.14
UNSPSC Code:
41116105
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
615586
Technique(s):
thin layer chromatography (TLC): suitable
InChI
1S/C6H6N4O4/c7-8-5-2-1-4(9(11)12)3-6(5)10(13)14/h1-3,8H,7H2
SMILES string
NNc1ccc(cc1[N+]([O-])=O)[N+]([O-])=O
InChI key
HORQAOAYAYGIBM-UHFFFAOYSA-N
concentration
~0.005 M in ethanol
technique(s)
thin layer chromatography (TLC): suitable
refractive index
n20/D 1.374
density
0.843 g/mL at 20 °C
suitability
in accordance for application
storage temp.
2-8°C
Quality Level
General description
2,4-二硝基苯肼盐酸溶液为衍生化试剂。
Application
2,4-二硝基苯肼盐酸盐溶液被用于对青蒿素衍生物进行薄层色谱检测。可用于羰基的测定。也可用于用预装药筒涂覆原位硅胶的步骤中。
signalword
Danger
hcodes
Hazard Classifications
Eye Irrit. 2 - Flam. Liq. 2 - Met. Corr. 1
存储类别
3 - Flammable liquids
wgk
WGK 2
flash_point_f
57.2 °F
flash_point_c
14.0 °C
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
法规信息
危险化学品
此项目有
R Fields et al.
The Biochemical journal, 121(4), 587-589 (1971-02-01)
A method is described for determining carbonyl groups that is especially suitable for use with proteins and peptides. It involves the determination of the extinction at 370nm of a sample solution after adding 2,4-dinitrophenylhydrazine. The reaction of 2,4-dinitrophenylhydrazine with pyruvoylglycine
Jean-Robert Ioset et al.
PloS one, 4(9), e7270-e7270 (2009-10-01)
Malaria continues to be one of the major public health problems in Africa, Asia and Latin America. Artemisinin derivatives (ARTs; artesunate, artemether, and dihydroartemisinin) derived from the herb, Artemisia annua, are the most effective antimalarial drugs available providing rapid cures.
S B Tejada
International journal of environmental analytical chemistry, 26(2), 167-185 (1986-01-01)
A procedure for coating in situ silica gel in prepacked cartridges with 2,4-dinitrophenylhydrazine (DNPH) acidified with hydrochloric acid is described. The coated cartridge was compared with a validated DNPH impinger method for sampling organic carbonyl compounds (aldehydes and ketones) in
[13C2]-Acetaldehyde promotes unequivocal formation of 1,N2-propano-2'-deoxyguanosine in human cells.
Camila Carrião M Garcia et al.
Journal of the American Chemical Society, 133(24), 9140-9143 (2011-05-25)
Acetaldehyde is an environmentally widespread genotoxic aldehyde present in tobacco smoke, vehicle exhaust and several food products. Endogenously, acetaldehyde is produced by the metabolic oxidation of ethanol by hepatic NAD-dependent alcohol dehydrogenase and during threonine catabolism. The formation of DNA
Laszlo Prokai et al.
Journal of chromatography. A, 1232, 281-287 (2012-02-22)
Carbonyl compounds are common byproducts of many metabolic processes. These volatile chemicals are usually derivatized before mass spectrometric analysis to enhance the sensitivity of their detections. The classically used reagent for this purpose is 2,4-dinitrophenylhydrazine (DNPH) that forms the corresponding
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