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22632

奎宁 盐酸盐 二水合物

tested according to Ph. Eur.

别名:

奎宁盐酸盐

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关于此项目

经验公式（希尔记法）:
C20H24N2O2 · HCl · 2H2O
化学文摘社编号:
6119-47-7
分子量:
396.91
UNSPSC Code:
12352210
NACRES:
NA.25
PubChem Substance ID:
329752329
EC Number:
205-001-1
Beilstein/REAXYS Number:
6112655
MDL number:
MFCD00151248
Form:
solid
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agency

tested according to Ph. Eur.

Quality Segment

form

solid

solubility

water: soluble 0.25 mg in 5 ml

application(s)

research use (small molecule)

SMILES string

O.O.Cl.COc1ccc2nccc([C@@H](O)[C@@H]3C[C@@H]4CCN3C[C@@H]4C=C)c2c1

InChI

1S/C20H24N2O2.ClH.2H2O/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;;;/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3;1H;2*1H2/t13-,14-,19-,20+;;;/m0.../s1

InChI key

MPQKYZPYCSTMEI-FLZPLBAKSA-N

Application

Quinine hydrochloride dehydrate has been used for fluorescent in situ detection of quinine in cinchona bark using UV resonance raman spectroscopy. It has also been used as a actinometric system to measure the light-induced changes in ruthenium anticancer agent, NAMI-A.

Biochem/physiol Actions

Quinine is a very effective anti-malarial treatment but is considered toxic for routine treatment due to the development of drug resistance in the malarial parasites. It acts as blood schizonticide.Quinine reportedly blocks the membrane conductance of potassium in enteric neurons.

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象形图

Health hazardExclamation mark
GHS08,GHS07

警示词

Danger

危险代码

H302,H317,H334

Hazard Classifications

Acute Tox. 4 Oral - Resp. Sens. 1 - Skin Sens. 1

存储类别

11 - Combustible Solids

闪点 (F)

Not applicable

闪点 (°C)

Not applicable

PPE（个人防护设备）

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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