产品名称
D -甘露醇, ≥99%
InChI
1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1
InChI key
FBPFZTCFMRRESA-KVTDHHQDSA-N
SMILES string
OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
assay
≥99%
optical activity
[α]25/D +141°, c = 0.4 in acidified ammonium molybdate
mp
167-170 °C (lit.)
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Biochem/physiol Actions
一种糖醇类甜味剂。 用于甜味抑制研究。
Other Notes
This product has been replaced by M4125-Sigma-Aldrich | D-Mannitol ≥98%
法规信息
新产品
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Christopher J Burns et al.
Bioorganic & medicinal chemistry letters, 19(20), 5887-5892 (2009-09-19)
A series of phenylaminopyrimidines has been identified as inhibitors of Janus kinases (JAKs). Development of this initial series led to the potent JAK2/JAK1 inhibitor CYT387 (N-(cyanomethyl)-4-[2-[[4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]-benzamide). Details of synthesis and SAR studies of these compounds are reported.
Markus Bollinger et al.
Journal of medicinal chemistry, 55(2), 871-882 (2011-12-22)
Intervention in integrin-mediated cell adhesion and integrin signaling pathways is an ongoing area of research in medicinal chemistry and drug development. One key element in integrin-ligand interaction is the coordination of the bivalent cation at the metal ion-dependent adhesion site
Tian-Rong Li et al.
European journal of medicinal chemistry, 43(8), 1688-1695 (2007-11-27)
Two novel rare earth complexes, Y(III) complex (1) and Eu(III) complex (2), with naringenin-2-hydroxy benzoyl hydrazone ligand were synthesized and characterized. The interaction of the two metal complexes and the free ligand with calf thymus DNA (CT DNA) was investigated
Shmuel Hess et al.
Journal of medicinal chemistry, 51(4), 1026-1034 (2008-01-29)
The tetrapeptide sequence His-Phe-Arg-Trp, derived from melanocyte-stimulating hormone (alphaMSH) and its analogs, causes a decrease in food intake and elevates energy utilization upon binding to the melanocortin-4 receptor (MC4R). To utilize this sequence as an effective agent for treating obesity
Susanne T Wessling et al.
Bioorganic & medicinal chemistry, 15(14), 4946-4950 (2007-05-15)
Caco-2 cell permeability and stability assays were used as an in vitro model to study the intestinal epithelial transport and stability of two analogues of thyrotropin-releasing hormone (TRH; Pyr-His-Pro-NH2). Peptide 1 (Pyr-His-Pro-D-glucopyranuronamide) was more permeable across the Caco-2 cell monolayer
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