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Merck
CN

27301

水杨酸

99.5-100.5% (calc. to the dried substance), meets analytical specification of Ph. Eur., BP, USP

别名:

2-羟基苯甲酸

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线性分子式:
2-(HO)C6H4CO2H
化学文摘社编号:
69-72-7
分子量:
138.12
NACRES:
NA.21
PubChem Substance ID:
24856524
UNSPSC Code:
12352100
EC Number:
200-712-3
MDL number:
MFCD00002439
Beilstein/REAXYS Number:
774890

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产品名称

水杨酸, meets analytical specification of Ph. Eur., BP, USP, 99.5-100.5% (calc. to the dried substance)

InChI key

YGSDEFSMJLZEOE-UHFFFAOYSA-N

InChI

1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)

SMILES string

OC(=O)c1ccccc1O

vapor density

4.8 (vs air)

vapor pressure

1 mmHg ( 114 °C)

assay

99.5-100.5% (calc. to the dried substance)

quality

meets analytical specification of Ph. Eur., BP, USP

impurities

residual solvents, complies
≤0.001% heavy metals (as Pb)
≤0.2% related subst. (HPLC)

ign. residue

≤0.05% (as SO4)

loss

≤0.3% loss on drying

bp

211 °C (lit.)

mp

158-161 °C (lit.)
158-161 °C

anion traces

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤200 mg/kg

suitability

complies for appearance of solution
complies for identity

application(s)

pharmaceutical (small molecule)

functional group

carboxylic acid

Quality Level

200

Gene Information

human ... ALB(213), PTPN1(5770)

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相关类别

Application

  • 农业中的盐度胁迫管理：研究表明施用水杨酸可缓解大麦的盐度胁迫，说明其增强作物耐盐性的作用，有助于可持续性农业发展(Hanif et al., 2024)。
  • 增强药物凝胶性能：研究硝酸纤维素延缓盐酸左氧氟沙星-水杨酸原位凝胶的渗透，说明其可用于增强药物递送系统，尤其是提高细菌感染治疗的疗效(Khaing et al., 2024)。
  • 醉茄内酯的生物技术生产：水杨酸被用作南非醉茄毛状根培养物的激活剂，极大促进醉茄内酯和酚酸类物质的生产，这两类物质因其治疗作用对医药领域意义重大 (Halder and Ghosh, 2024)。

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 2

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

314.6 °F - closed cup

flash_point_c

157 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCF1182
BCCK4644
BCCJ2315
BCCH9684
BCCG9763

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Rapid colorimetric determination of nitrate in plant tissue by nitration of salicylic acid1.
Cataldo DA, et al.
Communications in Soil Science and Plant Analysis, 6(1), 71-80 (1975)
Salicylic acid activates nitric oxide synthesis in Arabidopsis.
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Journal of Experimental Botany, 58(6), 1397-1405 (2007)
Yunlong Du et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(19), 7946-7951 (2013-04-25)
Removal of cargos from the cell surface via endocytosis is an efficient mechanism to regulate activities of plasma membrane (PM)-resident proteins, such as receptors or transporters. Salicylic acid (SA) is an important plant hormone that is traditionally associated with pathogen
S Zaugg et al.
Journal of chromatography. B, Biomedical sciences and applications, 752(1), 17-31 (2001-03-20)
Acetylsalicylic acid (Aspirin) is rapidly metabolized to salicylic acid (salicylate) and other compounds, including gentisic acid and salicyluric acid. Monitoring of salicylate and its metabolites is of toxicological, pharmacological and biomedical interest. Three capillary electrophoresis (CE) methods featuring alkaline aqueous
E Benfeldt et al.
Acta dermato-venereologica, 79(5), 338-342 (1999-09-24)
Our aim was to simultaneously investigate 2 techniques for in vivo sampling of peripheral compartment pharmacokinetics after systemic administration of acetylsalicylic acid. Ten volunteers were given 2 g acetylsalicylic acid orally. Blood samples and dialysates from 4 microdialysis probes inserted
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