27429
柠康酸酐
≥99.0% (T)
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关于此项目
经验公式（希尔记法）:
C5H4O3
化学文摘社编号:
分子量:
112.08
EC Number:
210-459-0
UNSPSC Code:
12162002
PubChem Substance ID:
Beilstein/REAXYS Number:
1835
MDL number:
InChI key
AYKYXWQEBUNJCN-UHFFFAOYSA-N
InChI
1S/C5H4O3/c1-3-2-4(6)8-5(3)7/h2H,1H3
SMILES string
CC1=CC(=O)OC1=O
vapor density
4 (vs air)
assay
≥99.0% (T)
refractive index
n20/D 1.472
bp
213-214 °C (lit.)
mp
6-10 °C (lit.)
density
1.247 g/mL at 25 °C (lit.)
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Other Notes
用于氨基（例如赖氨酸侧链）的可逆性封端；可用于核蛋白复合物的解离
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1
存储类别
8A - Combustible corrosive hazardous materials
wgk
WGK 3
flash_point_f
231.8 °F - closed cup
flash_point_c
111 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
新产品
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[49] Reaction of proteins with citraconic anhydride.
M Z Atassi et al.
Methods in enzymology, 25, 546-553 (1972-01-01)
P P Batra
The International journal of biochemistry, 23(12), 1375-1384 (1991-01-01)
The lysine residues were modified to varying degrees (50-91%) with citraconic anhydride to determine the extent of conformational change in ovalbumin. Major findings included: 1. Sixteen of the 20 lysine residues are located on the protein surface, while the remaining
Anthony S-Y Leong et al.
Pathology, 42(1), 77-81 (2009-12-23)
The introduction of heat-induced antigen retrieval has been a major milestone in diagnostic immunohistochemistry, enabling the application of many antibodies to fixed paraffin-embedded tissue sections. A number of important variables affect the preservation of tissue antigens, among which are analytical
Jian-Zhong Liu et al.
Protein engineering, design & selection : PEDS, 19(4), 169-173 (2006-02-03)
Horseradish peroxidase (HRP) was modified by maleic anhydride and citraconic anhydride. The thermal and organic solvent tolerances of native and modified enzyme were compared. These chemical modifications of HRP increased their thermostability both in aqueous buffer and some organic solvents
J K Shetty et al.
The Biochemical journal, 191(1), 269-272 (1980-10-01)
Modification of proteins with citraconic anhydride altered the electrostatic relationship between cationic epsilon-NH3+ groups of lysine residues of proteins and anionic phosphate groups of nucleic acids, thereby destabilizing the nucleoprotein complex. This procedure facilitated the separation of proteins from nucleic
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