30122
L-半胱氨酸 盐酸盐 一水合物
tested according to Ph. Eur.
别名:
L-盐酸半胱氨酸一水物
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关于此项目
线性分子式:
HSCH2CH(NH2)COOH · HCl · H2O
化学文摘社编号:
分子量:
175.63
UNSPSC Code:
12352209
PubChem Substance ID:
eCl@ss:
32160406
EC Number:
200-157-7
Beilstein/REAXYS Number:
5158059
MDL number:
产品名称
L-半胱氨酸 盐酸盐 一水合物, tested according to Ph. Eur.
InChI key
QIJRTFXNRTXDIP-JIZZDEOASA-N
InChI
1S/C3H7NO2S.ClH.H2O/c4-2(1-7)3(5)6;;/h2,7H,1,4H2,(H,5,6);1H;1H2/t2-;;/m0../s1
SMILES string
O.Cl.N[C@@H](CS)C(O)=O
agency
USP/NF
tested according to Ph. Eur.
assay
98.5-101.0%
form
solid
mp
176 °C
solubility
H2O: soluble 100 g/L at 25 °C
application(s)
pharmaceutical (small molecule)
Quality Level
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Biochem/physiol Actions
NMDA谷氨酸能受体拮抗剂。
Cysteine is a non-essential, thiol-containing amino acid that has protective effects in normal tissues. It is converted to glutathione that decreases the effects of chemotherapeutic and radiation agents. This might restrict the effect of therapeutic agents used for cancer treatment.
Application
L-Cysteine hydrochloride monohydrate was used in the synthesis of polycarbophil-cysteine conjugate.
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
J C Roberts
Amino acids, 8(2), 113-124 (1995-06-01)
The thiol-containing amino acid, cysteine, and its analogs are useful for a variety of protective applications, including protecting normal tissues against the unwanted side effects of cancer chemotherapeutic agents and radiation treatment. The protection can result from both direct action
M K Marschütz et al.
Pharmaceutical research, 17(12), 1468-1474 (2001-04-17)
To develop an oral controlled release system for insulin. The polymer-inhibitor conjugates carboxymethylcellulose (CMC)-Bowman-Birk inhibitor and CMC-elastatinal were homogenized with polycarbophil-cysteine conjugate, insulin, and mannitol, compressed to 2 mg microtablets and enteric coated with a polymethacrylate. The protective effect of
Matthew Oser et al.
Journal of cell science, 123(Pt 21), 3662-3673 (2010-10-26)
Invadopodia are matrix-degrading membrane protrusions in invasive carcinoma cells enriched in proteins that regulate actin polymerization. The on-off regulatory switch that initiates actin polymerization in invadopodia requires phosphorylation of tyrosine residues 421, 466, and 482 on cortactin. However, it is
Qinjian Zhao et al.
Human vaccines & immunotherapeutics, 10(3), 734-739 (2013-12-05)
Cryo-transmission electron microscopy (cryoTEM) is a powerful characterization method for assessing the structural properties of biopharmaceutical nanoparticles, including Virus Like Particle-based vaccines. We demonstrate the method using the Human Papilloma Virus (HPV) VLPs in GARDASIL®. CryoTEM, coupled to automated data
Jiahua Li et al.
American journal of physiology. Cell physiology, 305(2), C190-C196 (2013-05-17)
Claudins constitute a family of tight junction transmembrane proteins whose first extracellular loop (ECL1) determines the paracellular permeability and ion selectivity in epithelia. There are two cysteines in the ECL1 that are conserved among all claudins. We hypothesized that these
商品
Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.
抗氧化剂可保护生物系统免受含氧自由基和氧化还原过渡金属离子（如铁、铜和镉）引起的氧化损伤。
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