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Merck
CN

31437-M

碳酸氢钠

puriss. p.a., ACS reagent, reag. Ph. Eur., ≥99.7%

别名:

小苏打

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关于此项目

线性分子式:
NaHCO3
化学文摘社编号:
144-55-8
分子量:
84.01
UNSPSC Code:
12352300
NACRES:
NA.21
PubChem Substance ID:
329753766
EC Number:
205-633-8
Beilstein/REAXYS Number:
4153970
MDL number:
MFCD00003528
Assay:
≥99.7%
Form:
powder
Solubility:
H2O: 0.5 g/10 mL, clear, colorless, water: soluble 50 g/L

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InChI key

UIIMBOGNXHQVGW-UHFFFAOYSA-M

InChI

1S/CH2O3.Na/c2-1(3)4;/h(H2,2,3,4);/q;+1/p-1

SMILES string

[Na+].OC([O-])=O

grade

ACS reagent, puriss. p.a.

agency

reag. Ph. Eur.

assay

≥99.7%

form

powder

impurities

≤0.003% S-compounds (as SO4), ≤0.015% in water insoluble matters, ≤5 mg/kg ammonium (NH4), ≤50 mg/kg I red. matters (as SO2)

pH

≤8.6 (20 °C, 5%)

pKa (25 °C)

(1) 6.37, (2) 10.25 (carbonic acid)

solubility

H2O: 0.5 g/10 mL, clear, colorless, water: soluble 50 g/L

density

2.16 g/mL at 25 °C (lit.)

anion traces

chloride (Cl-): ≤0.003%, phosphate (PO43-): ≤10 mg/kg

cation traces

As: ≤0.0002%, Ca: ≤0.01%, Cd: ≤0.0005%, Co: ≤0.005%, Cu: ≤0.0005%, Fe: ≤0.0005%, K: ≤0.005%, Mg: ≤0.005%, Ni: ≤0.005%, Pb: ≤0.0005%, Zn: ≤0.0005%, heavy metals: ≤5 mg/kg (by ICP-OES)

suitability

complies for appearance of solution

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General description

Sodium bicarbonate is widely used as a physiological buffer. The pKa for bicarbonate ↔ carbonic acid reaction is 6.37. The pKa for bicarbonate ↔ carbonate reaction is 10.25.

Application

Sodium bicarbonate may be used to maintain 7.4pH in Iscove′s modified Dulbecco′s medium for growth of murine hybridoma cell culture. It may be employed as a component of RPMI-1640 liquid medium in a study.

存储类别

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number
STBK5585
STBK3638
STBJ8266

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D W Denning et al.
The Journal of antimicrobial chemotherapy, 40(3), 401-414 (1997-10-24)
Given the increased choice of therapeutic agents and the rising incidence of serious invasive disease, it is important that reliable in-vitro methods for detecting antifungal drug resistance in Aspergillus spp. are developed. Six clinical isolates of Aspergillus fumigatus, obtained from
S S Ozturk et al.
Biotechnology and bioengineering, 39(4), 418-431 (1992-02-20)
The influence of ammonia and lactate on cell growth, metabolic, and antibody production rates was investigated for murine hybridoma cell line 163.4G5.3 during batch culture. The specific growth rate was reduced by one-half in the presence of an initial ammonia

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