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31679

氯丙嗪 盐酸盐

VETRANAL®, analytical standard

别名:

2-氯-10-(3-二甲氨基丙基)吩噻嗪 盐酸盐, CPZ, 氯普马嗪

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关于此项目

经验公式（希尔记法）:
C17H19ClN2S · HCl
化学文摘社编号:
69-09-0
分子量:
355.33
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329753883
EC Number:
200-701-3
Beilstein/REAXYS Number:
3779989
MDL number:
MFCD00012654
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grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

Cl[H].CN(C)CCCN1c2ccccc2Sc3ccc(Cl)cc13

InChI

1S/C17H19ClN2S.ClH/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20;/h3-4,6-9,12H,5,10-11H2,1-2H3;1H

InChI key

FBSMERQALIEGJT-UHFFFAOYSA-N

Gene Information

human ... DRD2(1813), DRD3(1814), DRD4(1815), HTR2A(3356)

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相关类别

General description

盐酸氯丙嗪（CPZ）是一种抗精神病药物，属于吩噻嗪类抗精神病药组。它可用于治疗精神或人格障碍。

Application

CPZ可以作为标准品，通过化学计量学方法[例如经典最小二乘法（CLS）、主成分回归（PCR）和偏最小二乘法（PLS）]在玻璃碳电极上对抗精神病药物进行测定。
在血红蛋白和过氧化物酶的微量测定中替代联苯胺、邻联茴香胺和邻联甲苯胺。
有关合适仪器技术的更多信息，请参考产品′分析证书。如需进一步支持，请联系技术服务。

Biochem/physiol Actions

吩噻嗪类抗精神病药;D2 多巴胺受体拮抗剂，H1 组胺受体拮抗剂;抑制钙调蛋白依赖性环核苷酸磷酸二酯酶和一氧化氮合成酶的活化。
氯丙嗪表现出对白血病细胞的细胞毒性和抗增殖活性，但是不会影响正常淋巴细胞的活力。

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301,H330

Hazard Classifications

Acute Tox. 1 Inhalation - Acute Tox. 3 Oral

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCN8840
BCCF9060
BCBV3536
BCBS3655V

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全球贸易项目编号

货号GTIN
31679-250MG04061826691250

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