32138
Doripenem monohydrate
VETRANAL®, analytical standard
别名:
(4R,5S,6S)-6-[(1R)-1-Hydroxyethyl]-4-methyl-7-oxo-3-[(3S,5S)-5-[(sulfamoylamino)methyl]pyrrolidin-3-yl]sulfanyl-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
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关于此项目
经验公式（希尔记法）:
C15H24N4O6S2 · H2O
化学文摘社编号:
分子量:
438.52
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
15340136
grade
analytical standard
Quality Level
product line
VETRANAL®
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
veterinary
format
neat
storage temp.
2-8°C
SMILES string
[H]O[H].NS(NC[C@H](C1)NC[C@H]1SC2=C(C(O)=O)N3C([C@]([H])([C@H](O)C)[C@@]3([H])[C@H]2C)=O)(=O)=O
InChI
1S/C15H24N4O6S2.H2O/c1-6-11-10(7(2)20)14(21)19(11)12(15(22)23)13(6)26-9-3-8(17-5-9)4-18-27(16,24)25;/h6-11,17-18,20H,3-5H2,1-2H3,(H,22,23)(H2,16,24,25);1H2/t6-,7-,8+,9+,10-,11-;/m1./s1
InChI key
NTUBEBXBDGKBTJ-WGLOMNHJSA-N
General description
Doripenem belongs to the carbapenems family of β-lactam antibiotic compounds.
Application
Doripenem monohydrate can be used as the precursor for the preparation of doripenem which may be used as an analytical reference standard for the determination of doripenem in:
- Bovine muscle by liquid chromatography combined with tandem mass spectrometry (LC-MS/MS).
- Bulk drug and formulations by high performance thin layer chromatography (HPTLC).
- Medicinal products by capillary electrophoresis coupled to ultraviolet (UV) detector as well as micellar electrokinetic chromatography (MEKC) with UV detection.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
涉药品监管产品
此项目有
A validated HPTLC method for the determination of doripenem in pharmaceutical dosage forms.
Kurien J, et al.
International Journal of Pharmaceutical Sciences Review and Research, 27, 317-321 (2014)
Determination of biapenem in a medicinal product by micellar electrokinetic chromatography with sweeping in an enhanced electric field.
Michalska K, et al.
Journal of Chromatography A, 1282(4), 153-160 (2013)
Determination of doripenem and related substances in medicinal product using capillary electrophoresis.
Michalska K, et al.
Journal of Separation Science, 34(4), 475-482 (2011)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 32138-25MG | 04061826702260 |