32142
Pirbuterol acetate
VETRANAL®, analytical standard
别名:
(RS)-2-(tert-Butylamino)-1-(6-hydroxymethyl-5-hydroxy-2-pyridyl)ethanol acetate salt, 6-(2-tert-Butylamino-1-hydroxyethyl)-2-hydroxymethylpyridin-3-ol acetate
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所有图片(2)
About This Item
经验公式(希尔记法):
C12H20N2O3 · C2H4O2
CAS号:
分子量:
300.35
Beilstein:
13318829
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
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等级
analytical standard
质量水平
产品线
VETRANAL®
技术
HPLC: suitable
gas chromatography (GC): suitable
应用
forensics and toxicology
pharmaceutical (small molecule)
veterinary
包装形式
neat
SMILES字符串
N(C(C)(C)C)CC(O)c1nc(c(cc1)O)CO.OC(=O)C
InChI
1S/C12H20N2O3.C2H4O2/c1-12(2,3)13-6-11(17)8-4-5-10(16)9(7-15)14-8;1-2(3)4/h4-5,11,13,15-17H,6-7H2,1-3H3;1H3,(H,3,4)
InChI key
QSXMZJGGEWYVCN-UHFFFAOYSA-N
基因信息
human ... ADRB2(154)
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应用
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
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法律信息
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
11 - Combustible Solids
WGK
WGK 3
N E Robinson et al.
Equine veterinary journal, 32(5), 393-400 (2000-10-19)
During a trial to determine the dose response to the beta2-adrenergic agonist pirbuterol, we judged the severity of airway obstruction by use of a clinical scoring system and compared this to objective data obtained by quantitative measures of lung function.
Paradoxical asthma hazard of short-acting beta2-agonists.
M J Seed et al.
Allergy, 63(2), 241-241 (2007-11-22)
A E Carie et al.
Oncogene, 26(26), 3777-3788 (2007-01-30)
A chemical biology approach identifies a beta 2 adrenergic receptor (beta2AR) agonist ARA-211 (Pirbuterol), which causes apoptosis and human tumor regression in animal models. beta2AR stimulation of cAMP formation and protein kinase A (PKA) activation leads to Raf-1 (but not
R Silverman et al.
Chest, 114(3), 766-770 (1998-09-22)
Patients with acute asthma often have difficulty using a conventional metered-dose inhaler. The Maxair Autohaler (3M Pharmaceuticals; St. Paul, MN) is a hand-held breath-actuated device developed to help patients coordinate drug administration. The study objective is to compare the efficacy
Life-threatening asthma during treatment with salmeterol.
Miles Weinberger et al.
The New England journal of medicine, 355(8), 852-853 (2006-08-25)
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