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Merck
CN

32173

Ipronidazole

VETRANAL®, analytical standard

别名:

1-Methyl-2-(1-methylethyl)-5-nitro-1H-imidazole, 2-Isopropyl-1-methyl-5-nitroimidazol, NSC 109212, Ro 07-1554

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关于此项目

经验公式(希尔记法):
C7H11N3O2
化学文摘社编号:
分子量:
169.18
PubChem Substance ID:
UNSPSC Code:
41116107
NACRES:
NA.24
EC Number:
238-957-3
MDL number:
Beilstein/REAXYS Number:
744577
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产品名称

Ipronidazole, VETRANAL®, analytical standard

SMILES string

[N+](=O)([O-])c1[n](c(nc1)C(C)C)C

InChI key

NTAFJUSDNOSFFY-UHFFFAOYSA-N

InChI

1S/C7H11N3O2/c1-5(2)7-8-4-6(9(7)3)10(11)12/h4-5H,1-3H3

grade

analytical standard

product line

VETRANAL®

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
veterinary

format

neat

Quality Level

Application

Ipronidazole may be used as a reference standard in the determination of ipronidazole in tissue samples using high-performance liquid chromatography coupled with an ultraviolet detector (HPLC) and thermospray tandem mass spectrometry (HPLC-MS/MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

General description

Ipronidazole is a veterinary drug, which is widely used in controlling histomoniasis in turkeys.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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B Abbitt et al.
Journal of the American Veterinary Medical Association, 188(1), 67-69 (1986-01-01)
Two of 3 adult Greyhounds with clinical signs of giardiasis were treated by the addition of ipronidazole hydrochloride to their water supply (126 mg/L) for 7 days. Within 15 hours, the dogs had improved clinically, and large numbers of degenerating
Identification of dimetridazole, ipronidazole, and their alcohol metabolites in turkey tissues by thermospray tandem mass spectrometry.
Matusik EJ, et al.
Journal of Agricultural and Food Chemistry, 40(3), 439-443 (1992)
W J Morris et al.
Journal - Association of Official Analytical Chemists, 70(4), 630-634 (1987-07-01)
Extracts from 4 types of swine feed containing 0.11 ppm each of dimetridazole (DMZ) and ipronidazole (IPR) were analyzed by capillary gas chromatography/mass spectrometry (GC/MS) using multiple ion detection (MID) techniques. We demonstrate in this paper that the quantitative results
Determination of ipronidazole and its principal metabolite in turkey skin and muscle by combined gas chromatography-negative chemical ionization mass spectrometry-stable isotope dilution.
W A Garland et al.
Journal of agricultural and food chemistry, 28(2), 273-277 (1980-03-01)
J E Roybal et al.
Journal - Association of Official Analytical Chemists, 70(4), 626-630 (1987-07-01)
A simple and rapid method is described for the determination of dimetridazole (DMZ) and ipronidazole (IPR) in swine feeds at various levels (0.11-110 ppm). The drugs are released from feed by prewetting with a buffer, followed by extraction with either

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