32301-M
乙酸铵
puriss. p.a., ACS reagent, reag. Ph. Eur., ≥98%
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线性分子式:
CH3CO2NH4
化学文摘社编号:
分子量:
77.08
NACRES:
NA.21
PubChem Substance ID:
eCl@ss:
39021908
UNSPSC Code:
12352300
EC Number:
211-162-9
MDL number:
Beilstein/REAXYS Number:
4186741
Assay:
≥98%
Form:
solid
SMILES string
N.CC(O)=O
InChI key
USFZMSVCRYTOJT-UHFFFAOYSA-N
InChI
1S/C2H4O2.H3N/c1-2(3)4;/h1H3,(H,3,4);1H3
grade
ACS reagent, puriss. p.a.
agency
reag. Ph. Eur.
vapor pressure
<0.001 hPa
assay
≥98%
form
solid
impurities
≤0.0002% heavy metals (as Pb), ≤0.005% KMnO4 red. matter (as HCOOH), ≤2% water (Karl Fischer)
ign. residue
≤0.01% (as SO4)
pH
6.5-7.5 (25 °C, 77.1 g/L)
mp
110-112 °C (dec.) (lit.)
anion traces
chloride (Cl-): ≤5 mg/kg, nitrate (NO3-): ≤10 mg/kg, sulfate (SO42-): ≤10 mg/kg
cation traces
Ca: ≤10 ppm, Cd: ≤2 ppm, Co: ≤5 ppm, Cr: ≤5 ppm, Cu: ≤2 ppm, Fe: ≤2 ppm, K: ≤50 ppm, Mg: ≤2 ppm, Mn: ≤5 ppm, Na: ≤50 ppm, Ni: ≤5 ppm, Pb: ≤2 ppm, Zn: ≤2 ppm
Quality Level
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General description
Ammonium acetate is a colorless hygroscopic solid. It can be prepared by reacting glacial acetic acid with ammonia or ammonium carbonate. It has been reported as potential inhibitor of Pd/C mediated hydrogenolysis of benzyl ether.
Application
Ammonium acetate has been used in the mobile phase for the HPLC determination of ezetimibe and its metabolites. It may be used in preparation of phenanthrimidazoles and retinimidazoles.
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Anima Ghosal et al.
Drug metabolism and disposition: the biological fate of chemicals, 32(3), 314-320 (2004-02-24)
Ezetimibe [1-(4-fluorophenyl)-3(R)-[3-(4-fluorophenyl)-3(S)-hydroxypropyl]-4(S)-(4-hydroxyphenyl)-2-azetidinone] (Zetia; Schering-Plough, Kenilworth, NJ) is the first in a new class of cholesterol-lowering agents known as cholesterol absorption inhibitors. The objective of this study was to identify the isoform(s) of human liver and intestinal UDP-glucuronosyltransferase (UGT) enzymes responsible
Reactions of phenanthraquinone and retenequinone with aldehydes and ammonium acetate in acetic acid solution1.
Steck EA and Day AR.
Journal of the American Chemical Society, 65(3), 452-456 (1943)
Selective inhibition of benzyl ether hydrogenolysis with Pd/C due to the presence of ammonia, pyridine or ammonium acetate.
Sajiki H.
Tetrahedron Letters, 36(20), 3465-3468 (1995)
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