32402
磺胺胍
VETRANAL®, analytical standard
别名:
4-氨基-N-(氨基亚氨基甲基)苯磺酰胺, 4-氨基-N-胍基苯磺酰胺
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关于此项目
经验公式（希尔记法）:
C7H10N4O2S
化学文摘社编号:
分子量:
214.24
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
200-345-9
Beilstein/REAXYS Number:
2695326
MDL number:
InChI
1S/C7H10N4O2S/c8-5-1-3-6(4-2-5)14(12,13)11-7(9)10/h1-4H,8H2,(H4,9,10,11)
InChI key
BRBKOPJOKNSWSG-UHFFFAOYSA-N
SMILES string
NC(=N)NS(=O)(=O)c1ccc(N)cc1
grade
analytical standard
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
clinical testing
format
neat
Quality Level
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General description
Chemical structure: sulfonamide
Sulfaguanidine belongs to the sulfonamide class of antibiotics. It can exhibit broad-spectrum inhibition of both gram-positive and gram-negative bacteria.
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Sulfaguanidine may be used as an analytical reference standard for the determination of sulfaguanidine in:
- Food samples of animal origin by salting-out supported liquid extraction (SOSLE) and quick, easy, cheap, effective, rugged and safe (QuEChERS) extraction followed by analysis using nanoflow liquid chromatography high resolution mass spectrometry (LC-HRMS).
- Bovine muscle samples by hydrophilic interaction liquid chromatography-electrospray-tandem mass spectrometry (HILIC-ESI-MS/MS) equipped with selected reaction monitoring (SRM) mode of detection.
- Tissues, milk and eggs of food producing animals by ultrasound-assisted extraction (UAE), solid phase extraction (SPE) and LC-MS/MS.
- Beeswax by solid-liquid extraction (SLE), liquid-liquid extraction (LLE), SPE, QuEChERS extraction and ESI-LC-MS/MS with SRM detection.
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
wgk
WGK 3
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
Determination of sulfonamides in beeswax by liquid chromatography coupled to tandem mass spectrometry.
Mitrowska K and Antczak M
Journal of Chromatography. B, Biomedical Sciences and Applications, 1006, 179-186 (2015)
Determination of sulfonamides in serum by on-line solid-phase extraction coupled to liquid chromatography with photoinduced fluorescence detection.
Arroyo-Manzanares N, et al.
Talanta, 138, 258-262 (2015)
Vimal K Balakrishnan et al.
Journal of chromatography. A, 1131(1-2), 1-10 (2006-08-02)
In recent years, pharmaceutical and personal care products (PPCPs) have been detected in diverse environments (including groundwater, river water, and municipal wastewater). In order to evaluate their environmental impact, PPCPs must first be accurately determined. In this study, we focused
H Sasaki et al.
Journal of pharmacobio-dynamics, 13(3), 200-205 (1990-03-01)
The enhancing effect of pyrrolidone derivatives on the percutaneous penetration of sulfaguanidine, aminopyrine and sudan III was investigated using in vitro technique and excised rat skin. 1-Methyl (MP), 1-hexyl (HP) and 1-lauryl-2-pyrrolidone (LP) were used as penetration enhancers. Aminopyrine showed
Qualitative screening of veterinary anti-microbial agents in tissues, milk, and eggs of food-producing animals using liquid chromatography coupled with tandem mass spectrometry.
Chen D, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 1017, 82-88 (2016)
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