32438
帕苯达唑
VETRANAL®, analytical standard
别名:
(5-丁基-1H-苯并咪唑-2-基)氨基甲酸甲酯, 5(6)-丁基-2-苯并咪唑氨基甲酸甲酯
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关于此项目
经验公式（希尔记法）:
C13H17N3O2
化学文摘社编号:
分子量:
247.29
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
等级
analytical standard
质量水平
产品线
VETRANAL®
保质期
limited shelf life, expiry date on the label
技术
HPLC: suitable
gas chromatography (GC): suitable
应用
forensics and toxicology
pharmaceutical (small molecule)
包装形式
neat
储存温度
2-8°C
SMILES字符串
CCCCc1ccc2nc(NC(=O)OC)[nH]c2c1
InChI
1S/C13H17N3O2/c1-3-4-5-9-6-7-10-11(8-9)15-12(14-10)16-13(17)18-2/h6-8H,3-5H2,1-2H3,(H2,14,15,16,17)
InChI key
YRWLZFXJFBZBEY-UHFFFAOYSA-N
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一般描述
Parbendazole is a carbamate ester-amine. It finds applications in control or treatment of nematode infestations.
应用
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
法律信息
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral - Repr. 2
储存分类代码
11 - Combustible Solids
WGK
WGK 3
D R Hennessy et al.
Journal of veterinary pharmacology and therapeutics, 15(1), 10-18 (1992-03-01)
The effect of intraruminal administration of parbendazole (PBZ) on the flow rate of bile and the pharmacokinetic behaviour of oxfendazole (OFZ) was examined in sheep. PBZ given at 18, 9 and 4.5 mg/kg resulted in a dose-related reduction in bile
E Lacey et al.
Molecular and biochemical parasitology, 19(2), 171-181 (1986-05-01)
The binding of tritiated benzimidazoles (BZs)-albendazole, parbendazole, oxibendazole, mebendazole, oxfendazole and fenbendazole-to crude tubulin extracts from BZ-susceptible and -resistant Haemonchus contortus has been examined. For all BZs, the binding was substantially lower in the resistant isolate. The extent of this
Hiroshi Sato et al.
The Journal of veterinary medical science, 65(4), 453-457 (2003-05-09)
Larva migrans caused by the common raccoon ascarid, Baylisascaris procyonis, is a zoonotic disease of critical importance in North America. Recently we encountered the first proven outbreak of this disease in Japan in domestic rabbits (Oryctolagus cuniculus) in a small
K E Foster et al.
European journal of biochemistry, 163(3), 449-455 (1987-03-16)
The mutant BEN210 of Physarum polycephalum is highly resistant to a number of benzimidazole carbamate agents, including methylbenzimidazole-2-yl-carbamate and parbendazole. The resistance is conferred by the benD210 mutation in a structural gene for beta-tubulin. This mutant allele encodes a beta-tubulin
N C Sangster et al.
The Journal of parasitology, 71(5), 645-651 (1985-10-01)
Benzimidazole treatment produced greater effects on microtubule-dependent acetylcholinesterase secretion, the presence of microtubules in intestinal cells, and colchicine binding in susceptible compared with benzimidazole-resistant Trichostrongylus colubriformis. In addition, the binding of benzimidazoles was markedly reduced in preparations from the latter
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