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Merck
CN

32502

Sigma-Aldrich

8-羟基喹啉

puriss. p.a., ACS reagent, reag. Ph. Eur., ≥99% (perchloric acid titration)

别名:

8-氢氧化喹啉, 8-羟基氮杂萘, 喔星

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关于此项目

经验公式（希尔记法）:
C9H7NO
CAS Number:
148-24-3
分子量:
145.16
Beilstein:
114512
EC 号:
205-711-1
MDL编号:
MFCD00006807
UNSPSC代码:
12352100
PubChem化学物质编号:
57648688
NACRES:
NA.21

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等级

ACS reagent
puriss. p.a.

质量水平

200

Agency

reag. Ph. Eur.

方案

≥99% (perchloric acid titration)

表单

solid

技术

titration: suitable

杂质

≤0.05% insoluble in ethanol

灼烧残渣

≤0.05% (as SO4)

mp

72.5-74.0 °C
72.5-75 °C

痕量阴离子

chloride (Cl-): ≤10 mg/kg
sulfate (SO42-): ≤100 mg/kg

适用性

passes test for suitability for Mg decision

抗生素抗菌谱

fungi

作用机制

DNA synthesis | interferes
enzyme | inhibits

SMILES字符串

Oc1cccc2cccnc12

InChI

1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H

InChI key

MCJGNVYPOGVAJF-UHFFFAOYSA-N

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一般描述

8-Quinolinol (QOH) forms complexes with heavy metals [Pt(II), Pb(II), Bi(III), Ir(III)]. These complexes show long-lived phosphorescence and excited state absorption in solutions. It has been reported to form metal chelate complexes. Immobilized 8-quinolinol has been widely used in the preconcentration step during the extraction of metals.
Chemical structure: quinolone

警示用语：

Danger

危险分类

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Repr. 1B - Skin Sens. 1

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCN6403
BCCJ9270
BCCD9368
BCCC2732
BCCC1726

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Synthesis of silica-immobilized 8-quinolinol with (aminophenyl) trimethoxysilane.
Marshall MA and Mottola HA.
Analytical Chemistry, 55(13), 2089-2093 (1983)
Phosphorescent 8-quinolinol metal chelates. Excited-state properties and redox behavior.
Ballardini R, et al.
Inorganic Chemistry, 25(22), 3858-3865 (1986)
The reactions of 8-quinolinol.
Phillips JP.
Chemical Reviews, 56(2), 271-297 (1956)
Synthesis, crystal structure and spectral properties of VO (acetylacetone benzoylhydrazone)(8-quinolinol).
Liu SX and Gao S.
Polyhedron, 17(1), 81-84 (1998)
María Isabel Fernández-Bachiller et al.
Journal of medicinal chemistry, 53(13), 4927-4937 (2010-06-16)
Tacrine and PBT2 (an 8-hydroxyquinoline derivative) are well-known drugs that inhibit cholinesterases and decrease beta-amyloid (Abeta) levels by complexation of redox-active metals, respectively. In this work, novel tacrine-8-hydroxyquinoline hybrids have been designed, synthesized, and evaluated as potential multifunctional drugs for
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