32553
替硝唑
VETRANAL®, analytical standard
别名:
1-[2-(乙磺酰基)乙基]-2-甲基-5-硝基咪唑
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关于此项目
经验公式（希尔记法）:
C8H13N3O4S
化学文摘社编号:
分子量:
247.27
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
243-014-4
Beilstein/REAXYS Number:
618182
MDL number:
产品名称
替硝唑, VETRANAL®, analytical standard
Quality Level
InChI
1S/C8H13N3O4S/c1-3-16(14,15)5-4-10-7(2)9-6-8(10)11(12)13/h6H,3-5H2,1-2H3
InChI key
HJLSLZFTEKNLFI-UHFFFAOYSA-N
SMILES string
CCS(=O)(=O)CCn1c(C)ncc1[N+]([O-])=O
grade
analytical standard
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
format
neat
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Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Tinidazole may be used as an analytical reference standard for the determination of the analyte in:
- Tablet formulations and human serum samples by reversed phase-high performance liquid chromatography (RP-HPLC).
General description
Tinidazole belongs to the family of nitroimidazole compounds.
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Carc. 2 - Muta. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Separation and assay o f antiprotozoal imidazole derivatives (metronidazole, tinidazole and secnidazole) by RP-HPLC.
Alhalabi Z, et al.
International Journal of Pharmaceutical Sciences Review and Research, 13(1), 13-18 (2012)
Multi-residue method for the detection of veterinary drugs in distillers grains by liquid chromatography-Orbitrap high resolution mass spectrometry.
Kaklamanos G, et al.
Journal of Chromatography A, 1322, 38-48 (2013)
Simultaneous estimation of ciprofloxacin hydrochloride, ofloxacin, tinidazole and ornidazole by reverse phase-high performance liquid chromatography.
Singh R, et al.
Eurasian Journal of Analytical Chemistry, 4(2), 161-167 (2009)
Elizabeth A Bosserman et al.
Sexually transmitted diseases, 38(10), 983-987 (2011-09-22)
Antimicrobial resistance is one of the causes of treatment failure in women after standard nitroimidazole therapy for Trichomonas vaginalis infections. The Centers for Disease Control and Prevention provides drug susceptibility testing and guidance for treatment failures but the efficacy of
Sanjay K Lanjhiyana et al.
Expert opinion on drug delivery, 10(1), 5-15 (2012-10-31)
The objective of this study is to develop stable, biodegradable chitosan-sodium alginate-based dual, ionic cross-linked multiparticulate system (microbeads) of tinidazole for targeted colon delivery and sustained drug release for the treatment of amoebiasis and thereby evaluating its targeting approach through
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