32591
巴喹普林
VETRANAL®, analytical standard
别名:
5-{[8-(二甲基氨基)-7-甲基-5-喹啉基]甲基}-2,4-嘧啶二胺
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关于此项目
经验公式（希尔记法）:
C17H20N6
化学文摘社编号:
分子量:
308.38
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
InChI
1S/C17H20N6/c1-10-7-11(8-12-9-21-17(19)22-16(12)18)13-5-4-6-20-14(13)15(10)23(2)3/h4-7,9H,8H2,1-3H3,(H4,18,19,21,22)
SMILES string
CN(C)c1c(C)cc(Cc2cnc(N)nc2N)c3cccnc13
InChI key
AIOWJIMWVFWROP-UHFFFAOYSA-N
grade
analytical standard
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
format
neat
Quality Level
General description
Baquiloprim is a diaminopyrimidine derivative used as an antibiotic in veterinary medicine.
Application
Baquiloprim may be used as an analytical reference standard for the determination of the analyte in:
- Bovine muscle samples by solid-phase extraction (SPE) and hydrophilic interaction liquid chromatography–tandem mass spectrometry (HILIC-MS/MS).
- Sewage sludge samples by QuEChERS (quick, easy, cheap, effective, rugged and safe) extraction and liquid chromatography coupled to time-of-flight mass spectrometry (LC-TOF-MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
G White et al.
Research in veterinary science, 54(3), 372-378 (1993-05-01)
During examination of the half-lives in cattle of a series of 5-substituted diaminobenzyl-pyrimidines, it was found that replacement of the phenyl ring of trimethoprim (TMP) by bicyclic structures, particularly a quinolyl group, led to increases in half-life. The presence of
Microbial screening methods for detection of antibiotic residues in slaughter animals.
Pikkemaat M.
Analytical and Bioanalytical Chemistry, 395(4), 893-905 (2009)
D G White et al.
The Veterinary record, 143(10), 273-276 (1998-10-27)
Thirty-eight, one- to two-week-old calves with experimentally induced Escherichia coli diarrhoea were randomly assigned to three treatment groups. Two groups of 15 calves were treated intramuscularly once daily for three days with either danofloxacin mesylate at 1.25 mg/kg bodyweight, or
Analysis of 76 veterinary pharmaceuticals from 13 classes including aminoglycosides in bovine muscle by hydrophilic interaction liquid chromatography-tandem mass spectrometry.
Dasenaki ME, et al.
Journal of Chromatography A, 1452(4), 67-80 (2016)
C Svensson et al.
Applied parasitology, 37(3), 168-176 (1996-09-01)
The excretion of Eimeria oocysts, the faecal dry matter and the weight gain of three groups of 12 calves, were compared during their first 20 days of grazing on a pasture known to have been contaminated with oocysts of Eimeria
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