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Merck
CN

32593

坎苯达唑

VETRANAL®, analytical standard

别名:

2-(4-噻唑基)-5-苯并咪唑氨基甲酸异丙酯

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关于此项目

经验公式(希尔记法):
C14H14N4O2S
化学文摘社编号:
分子量:
302.35
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
247-459-5
Beilstein/REAXYS Number:
563292
MDL number:
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产品名称

坎苯达唑, VETRANAL®, analytical standard

InChI key

QZWHWHNCPFEXLL-UHFFFAOYSA-N

InChI

1S/C14H14N4O2S/c1-8(2)20-14(19)16-9-3-4-10-11(5-9)18-13(17-10)12-6-21-7-15-12/h3-8H,1-2H3,(H,16,19)(H,17,18)

SMILES string

CC(C)OC(=O)Nc1ccc2[nH]c(nc2c1)-c3cscn3

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

Quality Level

Application

Cambendazole may be used as an analytical reference standard for the determination of the analyte in:
  • Bovine muscle samples by ultra-high performance liquid chromatography (UHPLC) coupled to tandem mass spectrometry (MS/MS) operating in ESI mode.
  • Bovine milk samples by LC-ESI-MS.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

General description

Cambendazole is classified under the family of benzimidazole anthelmintic compounds.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Health hazard

signalword

Warning

hcodes

Hazard Classifications

Repr. 2

存储类别

11 - Combustible Solids

wgk

WGK 3


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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H J Bürger et al.
The Veterinary record, 120(13), 293-296 (1987-03-28)
In order to confirm benzimidazole resistance as recommended at a workshop of the Commission of the European Communities the isolate 'E' of cyathostome strongyles originating from a stud where benzimidazole resistance had been demonstrated by egg hatch tests and by
Determination of benzimidazoles and levamisole residues in milk by liquid chromatography-mass spectrometry: screening method development and validation.
Jedziniak P, et al.
Journal of Chromatography A, 1216(46), 8165-8172 (2009)
C Bauer et al.
Veterinary parasitology, 21(3), 189-203 (1986-08-01)
The prevalence of benzimidazole-resistant small strongyles was determined in a survey, conducted on 14 thoroughbred studs, which compared the faecal egg counts of groups of horses before and after treatment with the recommended doses of cambendazole (20 mg kg-1 b.w.)
Nader S Abutaleb et al.
Antimicrobial agents and chemotherapy, 64(6) (2020-04-08)
Clostridioides difficile, the leading cause of nosocomial infections, is an urgent health threat worldwide. The increased incidence and severity of disease, the high recurrence rates, and the dearth of effective anticlostridial drugs have created an urgent need for new therapeutic
F H Borgsteede et al.
Veterinary parasitology, 68(1-2), 113-117 (1997-01-01)
The efficacy of treatment with cambendazole was tested in 1-year-old horses on a farm in Dubrovka, Ukraine. Thirty-five horses were treated. Their egg output was compared on the day of treatment and 14 days later with that of 33 untreated

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