32671
卡硝唑
VETRANAL®, analytical standard
别名:
[2-(2-甲基-5-硝基-咪唑-1-基)乙基]硫代氨基甲酸 O-甲酯
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关于此项目
经验公式（希尔记法）:
C8H12N4O3S
化学文摘社编号:
分子量:
244.27
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
255-663-0
Beilstein/REAXYS Number:
620260
MDL number:
产品名称
卡硝唑, VETRANAL®, analytical standard
InChI key
OVEVHVURWWTPFC-UHFFFAOYSA-N
InChI
1S/C8H12N4O3S/c1-6-10-5-7(12(13)14)11(6)4-3-9-8(16)15-2/h5H,3-4H2,1-2H3,(H,9,16)
SMILES string
COC(=S)NCCn1c(C)ncc1[N+]([O-])=O
grade
analytical standard
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
veterinary
format
neat
Quality Level
Application
Carnidazole may be used as an analytical reference standard for the determination of the analyte in:
- Eggs by liquid chromatography-tandem mass spectrometry (LC-MS/MS).
- Environmental water samples by dispersive liquid-liquid microextraction (DLLME), followed by micellar electrokinetic chromatography (MEKC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
General description
Carnidazoles belong to the class of nitroimidazole compounds that are generally utilized for the treatment of various diseases in poultry, cattle and pigs.
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Skin Sens. 1
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
Benjamin M Dudek et al.
Journal of wildlife diseases, 54(4), 755-764 (2018-06-05)
Avian trichomonosis, caused by the protozoan Trichomonas gallinae, affects bird-eating raptors worldwide. Raptors can develop trichomonosis by feeding on infected prey, particularly Rock Pigeons (C olumba livia), which are a reservoir for T. gallinae. Raptors may be particularly vulnerable to
Development and validation of a rapid method for the determination and confirmation of 10 nitroimidazoles in animal plasma using liquid chromatography tandem mass spectrometry.
Cronly M, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 877(14-15), 1494-1500 (2009)
Novel cation selective exhaustive injection-sweeping procedure for 5-nitroimidazole determination in waters by micellar electrokinetic chromatography using dispersive liquid-liquid microextraction.
Hernandez-Mesa, et al.
Journal of Chromatography A, 1341(46), 65-72 (2014)
F F Franssen et al.
Journal of veterinary pharmacology and therapeutics, 15(4), 409-415 (1992-12-01)
Six out of eight different Trichomonas gallinae strains isolated from racing pigeons proved to be resistant to the nitroimidazole drugs ronidazole, carnidazole and metronidazole. The minimal cytocidal concentration of ronidazole was determined in in vitro experiments. Moreover, a therapeutic dose
P Chaudhuri et al.
European journal of obstetrics, gynecology, and reproductive biology, 10(5), 325-328 (1980-06-01)
A double-blind controlled clinical trial of the new, not yet commercially available drug, carnidazole and tinidazole, was carried out in 77 women with a proven vaginal trichomoniasis. 39 patients and their sexual partners received a single dose of 2 g
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