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Merck
CN

32756

黄曲霉素 G1

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经验公式(希尔记法):
C17H12O7
化学文摘社编号:
分子量:
328.27
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
EC Number:
214-615-9
Beilstein/REAXYS Number:
1299768
MDL number:
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InChI

1S/C17H12O7/c1-20-9-6-10-12(8-3-5-22-17(8)23-10)14-11(9)7-2-4-21-15(18)13(7)16(19)24-14/h3,5-6,8,17H,2,4H2,1H3

InChI key

XWIYFDMXXLINPU-UHFFFAOYSA-N

SMILES string

COc1cc2OC3OC=CC3c2c4OC(=O)C5=C(CCOC5=O)c14

grade

analytical standard, reference material

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

storage temp.

−20°C

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General description

Aflatoxins are mycotoxins that are generated as a result of secondary metabolism of various fungal species such as Aspergillus, Penicillium and Fusarium.

Application

Aflatoxin G1 may be used as an analytical reference standard for the determination of aflatoxin G1 in:
  • Animal feed by high performance liquid chromatography with fluorescence detection (HPLC-FLD), as well as quick, easy, cheap, effective, rugged and safe (QuEChERS) extraction method combined with ultra-high performance liquid chromatography-high resolution mass spectrometry (UHPLC-HRMS).
  • Eggs by QuEChERS extraction method followed by analysis using UHPLC with tandem mass spectrometry (MS/MS) operating on electrospray ionization interface (ESI) mode.
  • Brazil nuts by immunoaffinity column (IAC) clean-up and HPLC-FLD
  • Plant-based milk and dairy products by dispersive liquid-liquid microextraction (DLLME), QuEChERS extraction method and HPLC-FLD.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Disclaimer

可能致癌。

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Carc. 1B - Muta. 1B

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P2 (EN 143) respirator cartridges

法规信息

高风险级别生物产品--毒素类产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Rapid and automated analysis of aflatoxin M1 in milk and dairy products by online solid phase extraction coupled to ultra-high-pressure-liquid-chromatography tandem mass spectrometry.
Campone L, et al.
Journal of Chromatography A, 1428, 212-219 (2016)
Target analysis and retrospective screening of veterinary drugs, ergot alkaloids, plant toxins and other undesirable substances in feed using liquid chromatography-high resolution mass spectrometry.
Leon N, et al.
Talanta, 149(1), 43-52 (2016)
Extended validation of a sensitive and robust method for simultaneous quantification of aflatoxins B1, B2, G1 and G2 in Brazil nuts by HPLC-FLD.
Campos WEO, et al.
J. Food Compos. Anal., 60(10), 90-96 (2017)
Haitao Shen et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(9), 3222-3228 (2012-06-20)
Our previous studies showed intragastric administration of Aflatoxin G(1) (AFG(1)) could induce lung adenocarcinoma, which derived from alveolar type II cells (AT-II cells). AT-II cells contribute to Aflatoxin B(1) (AFB(1)) metabolism and also serve as the potential progenitor cells for
Ahmed M Abdel-Hadi et al.
Toxins, 3(6), 647-659 (2011-11-10)
Aspergillus flavus and Aspergillus parasiticus are important pathogens of cotton, corn, peanuts and other oil-seed crops, producing toxins both in the field and during storage. We have designed three siRNA sequences (Nor-Ia, Nor-Ib, Nor-Ic) to target the mRNA sequence of

实验方案

LC/MS/MS Analysis of Aflatoxins in Hops on Ascentis® Express 2.7 μm Phenyl-Hexyl after Cleanup Using Supel™ Tox AflaZea SPE

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