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Merck
CN

32842

甲苯哒唑-d3

VETRANAL®, analytical standard

别名:

5-苯甲酰-2-苯并咪唑氨基甲酸甲基-d3 酯, 甲基-d3 N-(5-苯甲酰-1H-苯并咪唑-2-基)氨基甲酸酯

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关于此项目

经验公式(希尔记法):
C16D3H10N3O3
化学文摘社编号:
分子量:
298.31
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
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产品名称

甲苯哒唑-d3, VETRANAL®, analytical standard

InChI

1S/C16H13N3O3/c1-22-16(21)19-15-17-12-8-7-11(9-13(12)18-15)14(20)10-5-3-2-4-6-10/h2-9H,1H3,(H2,17,18,19,21)/i1D3

SMILES string

[2H]C([2H])([2H])OC(=O)Nc1nc2cc(ccc2[nH]1)C(=O)c3ccccc3

InChI key

OPXLLQIJSORQAM-FIBGUPNXSA-N

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

mass shift

M+3

Quality Level

Application

Mebendazole-d3 may be used as an internal standard for the determination of mebendazole in milk and animal muscle tissue samples by ultra-high performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS). It can also be used as an internal standard for the determination of levamisole and aminorex in biological samples by liquid chromatography hybrid quadrupole time-of-flight high-resolution mass spectrometry (LC-QTOF-HRMS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

General description

Mebendazole-d3 is a deuterated compound of anthelmintic drug, mebendazole.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Metabolism of levamisole and kinetics of levamisole and aminorex in urine by means of LC-QTOF-HRMS and LC-QqQ-MS.
Hess C, et al.
Analytical and Bioanalytical Chemistry, 405(12), 4077-4088 (2013)
Multiresidue method for identification and quantification of avermectins, benzimidazoles and nitroimidazoles residues in bovine muscle tissue by ultra-high performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS) using a QuEChERS approach.
da Silva GR, et al.
Talanta, 171(27), 307-320 (2017)
Ji Sun Lee et al.
PloS one, 12(1), e0169597-e0169597 (2017-01-14)
A confirmatory and quantitative method of liquid chromatography-tandem mass spectrometry (LC-MS/MS) for the determination of mebendazole and its hydrolyzed and reduced metabolites in pork, chicken, and horse muscles was developed and validated in this study. Anthelmintic compounds were extracted with
Determination of anthelmintic drug residues in milk using ultra high performance liquid chromatography-tandem mass spectrometry with rapid polarity switching.
Whelan M, et al.
Journal of Chromatography A, 1217(27), 4612-4622 (2010)

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