33262
1,3-二氨基-2-丙醇
purum, ≥96.5% (GC)
别名:
1,3-二氨基-2-羟基丙烷
等级
purum
质量水平
方案
≥96.5% (GC)
表单
solid
杂质
≤2.0% water
mp
40-44 °C (lit.)
溶解性
water: soluble 1 g/10 mL
官能团
amine
hydroxyl
储存温度
2-8°C
SMILES字符串
NCC(O)CN
InChI
1S/C3H10N2O/c4-1-3(6)2-5/h3,6H,1-2,4-5H2
InChI key
UYBWIEGTWASWSR-UHFFFAOYSA-N
基因信息
rat ... Grin2a(24409)
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应用
1,3-Diamino-2-propanol was used in the synthesis of poly(2-hydroxypropylene imine), poly(2-hydroxypropylene imine ethylene imine) and poly(hydroxypropylene imine propylene imine). It was also used in the synthesis of tetranuclear mixed ligand copper(II) complex of a pyrazole containing Schiff base and a hydroxyhexahydropyrimidylpyrazole group.
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Sachindranath Pal et al.
Inorganic chemistry, 44(11), 3880-3889 (2005-05-24)
A tetranuclear mixed ligand copper(II) complex of a pyrazole containing Schiff base and a hydroxyhexahydropyrimidylpyrazole and copper(II) and nickel(II) complexes of the Schiff base having N-donor atoms have been investigated. A 2 equiv amount of 5-methyl-3-formylpyrazole (MPA) and 2 equiv
Y W Hu et al.
Canadian journal of physiology and pharmacology, 60(12), 1493-1498 (1982-12-01)
The effect of diaminopropanol, an inhibitor of polyamine synthesis, on the metabolic response of liver to insulin was studied in streptozotocin-diabetic rats. Insulin elicited a prompt and very marked increase in ornithine and S-adenosylmethionine decarboxylase activities and in putrescine concentration.
L Alhonen-Hongisto
The Biochemical journal, 190(3), 747-754 (1980-09-15)
1. The mechanism of stimulation of S-adenosylmethionine decarboxylase (EC 4.1.1.50) activity by inhibitors of ornithine decarboxylase (EC 4.1.1.17), namely dl-alpha-difluoromethylornithine, 1,3-diaminopropane and 1,3-diaminopropan-2-ol, was studied in Ehrlich ascites-tumour cells grown in suspension cultures. 2. Difluoromethylornithine and diaminopropane, although decreasing the
W A Schulz et al.
Biological chemistry Hoppe-Seyler, 370(7), 729-736 (1989-07-01)
The relationship between polyamines and the rate of protein synthesis was investigated in non-proliferating cells: primary cultures of adult rat hepatocytes maintained in serum-free media, and treated with dexamethasone or dexamethasone + insulin. During the second day of culture, polyamine
L Alhonen-Hongisto et al.
The Biochemical journal, 188(2), 491-501 (1980-05-15)
The anti-proliferative effects of 1,1'-[(methylethanediylidene)dinitrilo]diguanidine [methylglyoxal bis(guanylhydrazone)] and 1,1'-[(metHYLETHANEDIYLIDENE)dinitrilo]bis-(3-aminoguaNIDINE) HAVE BEEN STUDIED IN Ehrlich ascites carcinoma cells grown in suspension cultures. Both compounds are potent inhibitors of S-adenosyl-L-methionine decarboxylase from the tumour cells. In the presence of putrescine (but not
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