33262
1,3-二氨基-2-丙醇
purum, ≥96.5% (GC)
别名:
1,3-二氨基-2-羟基丙烷
等级
purum
质量水平
方案
≥96.5% (GC)
表单
solid
杂质
≤2.0% water
mp
40-44 °C (lit.)
溶解性
water: soluble 1 g/10 mL
官能团
amine
hydroxyl
储存温度
2-8°C
SMILES字符串
NCC(O)CN
InChI
1S/C3H10N2O/c4-1-3(6)2-5/h3,6H,1-2,4-5H2
InChI key
UYBWIEGTWASWSR-UHFFFAOYSA-N
基因信息
rat ... Grin2a(24409)
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应用
1,3-Diamino-2-propanol was used in the synthesis of poly(2-hydroxypropylene imine), poly(2-hydroxypropylene imine ethylene imine) and poly(hydroxypropylene imine propylene imine). It was also used in the synthesis of tetranuclear mixed ligand copper(II) complex of a pyrazole containing Schiff base and a hydroxyhexahydropyrimidylpyrazole group.
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Sachindranath Pal et al.
Inorganic chemistry, 44(11), 3880-3889 (2005-05-24)
A tetranuclear mixed ligand copper(II) complex of a pyrazole containing Schiff base and a hydroxyhexahydropyrimidylpyrazole and copper(II) and nickel(II) complexes of the Schiff base having N-donor atoms have been investigated. A 2 equiv amount of 5-methyl-3-formylpyrazole (MPA) and 2 equiv
M Mach et al.
The Biochemical journal, 202(1), 153-162 (1982-01-15)
Inhibitors of polyamine synthesis (alpha-methylornithine and 1,3-diaminopropan-2-ol) were used to study the relationship between polyamine synthesis and specific methylations of tRNA in Dictyostelium discoideum during vegetative growth. Polyamine concentrations were found to be 10 mM for putrescine, 1.6 mM for
L Alhonen-Hongisto et al.
The Biochemical journal, 188(2), 491-501 (1980-05-15)
The anti-proliferative effects of 1,1'-[(methylethanediylidene)dinitrilo]diguanidine [methylglyoxal bis(guanylhydrazone)] and 1,1'-[(metHYLETHANEDIYLIDENE)dinitrilo]bis-(3-aminoguaNIDINE) HAVE BEEN STUDIED IN Ehrlich ascites carcinoma cells grown in suspension cultures. Both compounds are potent inhibitors of S-adenosyl-L-methionine decarboxylase from the tumour cells. In the presence of putrescine (but not
J M Matés et al.
Biochemical pharmacology, 42(5), 1045-1052 (1991-08-08)
Ornithine decarboxylase (ODC) activity of Ehrlich carcinoma cells was increased more than 36-fold after being maintained for 3.5 hr in vitro in a special chamber which allowed continuous perifusion with 0.5 mM ornithine; if incubated in vitro without perifusion the
Y W Hu et al.
Canadian journal of physiology and pharmacology, 60(12), 1493-1498 (1982-12-01)
The effect of diaminopropanol, an inhibitor of polyamine synthesis, on the metabolic response of liver to insulin was studied in streptozotocin-diabetic rats. Insulin elicited a prompt and very marked increase in ornithine and S-adenosylmethionine decarboxylase activities and in putrescine concentration.
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