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经验公式(希尔记法):
C13H10BrCl2O2PS
化学文摘社编号:
分子量:
412.07
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
244-472-8
Beilstein/REAXYS Number:
2152663
MDL number:
InChI key
CVRALZAYCYJELZ-UHFFFAOYSA-N
InChI
1S/C13H10BrCl2O2PS/c1-17-19(20,9-5-3-2-4-6-9)18-13-8-11(15)10(14)7-12(13)16/h2-8H,1H3
SMILES string
COP(=S)(Oc1cc(Cl)c(Br)cc1Cl)c2ccccc2
grade
analytical standard
product line
PESTANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, NMR: suitable, gas chromatography (GC): suitable
mp
71-73 °C
suitability
passes test for identity (NMR)
application(s)
agriculture
environmental
format
neat
storage temp.
2-8°C
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相关类别
General description
Leptophos, an organophosphorus insecticide found to be persistent in the environment, shows neurotoxic effects in humans. Its mode of action for pest control involves the inhibition of acetylcholinesterase enzyme activity.
Application
Leptophos may be used as an analytical reference standard for the quantification of the analyte in vegetables using solid phase micro-extraction coupled with gas chromatography-flame photometric detector (SPME-GC-FPD).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Legal Information
PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Aquatic Acute 1 - Aquatic Chronic 1 - STOT SE 1
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
flash_point_f
>212.0 °F
flash_point_c
> 100 °C
法规信息
危险化学品
农药列管产品
此项目有
Determination of organophosphorus pesticide residues in vegetables using solid phase micro-extraction coupled with gas chromatography-flame photometric detector.
Sapahin AH, et al.
Arabian Journal of Chemistry, 23(1), 636-641 (2014)
Photodegradation of leptophos.
Riskallah RM, et al.
Bulletin of Environmental Contamination and Toxicology, 23(1), 636-641 (1979)
Y Yamaguchi
Nihon eiseigaku zasshi. Japanese journal of hygiene, 43(6), 1159-1168 (1989-02-01)
In an attempt to carry out a pharmacokinetic study of the organophosphorous insecticide leptophos, which is known to produce delayed neurotoxicity (DNT), a practical method for the analysis of leptophos in tissue samples has been developed by utilizing high-performance liquid
[Effect of the organophosphorus compounds leptophos and TOCP on creatine kinase activity in hens].
K Katoh et al.
Nihon eiseigaku zasshi. Japanese journal of hygiene, 42(4), 847-857 (1987-10-01)
J E Chambers et al.
Journal of biochemical toxicology, 4(3), 201-203 (1989-01-01)
The oxidative desulfuration of the three phosphorothionate insecticides--chlorpyrifos, chlorpyrifos-methyl, and leptophos--was studied in rat brain and liver. Hepatic microsomes demonstrated activities of 4-28 nmol/g/min, with male activity 2- to 4-fold higher than female activity. Very low desulfuration activity of all
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