33497
沙氟沙星 盐酸盐 水合物
VETRANAL®, analytical standard
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经验公式（希尔记法）:
C20H17F2N3O3 · HCl · xH2O
化学文摘社编号:
分子量:
421.83 (anhydrous basis)
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
SMILES string
Fc1ccc(cc1)N2c3c(cc(c(c3)N4CCNCC4)F)C(=O)C(=C2)C(=O)O.[Cl-].[H+]
InChI
1S/C20H17F2N3O3.ClH/c21-12-1-3-13(4-2-12)25-11-15(20(27)28)19(26)14-9-16(22)18(10-17(14)25)24-7-5-23-6-8-24;/h1-4,9-11,23H,5-8H2,(H,27,28);1H
InChI key
KNWODGJQLCISLC-UHFFFAOYSA-N
grade
analytical standard
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
format
neat
Quality Level
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Application
有关合适仪器技术的更多信息，请参考产品分析证书。如需进一步支持，请联系技术服务部门。
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves
E Rodriguez et al.
Journal of chromatography. A, 1209(1-2), 136-144 (2008-10-03)
This paper describes a new method for the effective extraction, clean-up and chromatographic analysis of residues of four fluoroquinolones (ciprofloxacin, enrofloxacin, danofloxacin and sarafloxacin) in powdered infant formulae and follow-on preparations. Samples were reconstituted following the manufacturer's recommendations and treated
Yan Z Liu et al.
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes, 48(2), 139-146 (2013-01-12)
The objective of this study was to produce a generic antibody for immunoassay of fluoroquinolone drugs in meat. Two novel haptens of sarafloxacin were synthesized that were used to produce the monoclonal antibodies. The obtained monoclonal antibodies simultaneously recognized 12
Ling-Ling Zhang et al.
Research in veterinary science, 90(1), 99-105 (2010-06-29)
The inhibitory effects of fluoroquinolones on the enzyme activity, protein levels and mRNA expression of liver cytochrome P450 (CYP) 1A and 3A were investigated in male broiler chicks. Enrofloxacin (20 mg/kg), sarafloxacin (8 mg/kg) and marbofloxacin (5.5 mg/kg) were administrated
Priscilla Henno et al.
American journal of physiology. Lung cellular and molecular physiology, 300(6), L831-L839 (2011-03-08)
Pulmonary vascular remodeling and dysfunction associated to tobacco smoking might pave the way for the subsequent development of pulmonary hypertension. Its prognosis is dreadful and its underlying mechanisms are so far largely unknown in humans. To assess the potential role
Jeong-Heui Choi et al.
Biomedical chromatography : BMC, 25(3), 405-411 (2010-07-06)
In this study, a method for the detection of sarafloxacin in pig and chicken muscles was developed using HPLC-FLD as a regulatory residue technique. Good extraction efficiency was achieved using a mixture of 1% orthophosphoric acid-0.2 m MgCl(2) in water
商品
LC-MS/MS-based determination of 19 sulfonamides, 13 quinolones, and 3 tetracycline drug residues in pork meat samples using Supel™ Swift HLB for extraction.
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