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Merck
CN

33626

对氨基苯磺酰胺

≥98% (calc. to the dried substance), solid, purum p.a.

别名:

对氨基苯磺酰胺

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关于此项目

线性分子式:
H2NC6H4SO2NH2
化学文摘社编号:
63-74-1
分子量:
172.20
NACRES:
NA.21
PubChem Substance ID:
57648871
eCl@ss:
39093202
UNSPSC Code:
12352100
EC Number:
200-563-4
MDL number:
MFCD00007939
Beilstein/REAXYS Number:
511852

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产品名称

对氨基苯磺酰胺, puriss. p.a., ≥98% (calc. to the dried substance)

InChI key

FDDDEECHVMSUSB-UHFFFAOYSA-N

InChI

1S/C6H8N2O2S/c7-5-1-3-6(4-2-5)11(8,9)10/h1-4H,7H2,(H2,8,9,10)

SMILES string

Nc1ccc(cc1)S(N)(=O)=O

grade

puriss. p.a.

assay

≥98% (calc. to the dried substance)

form

solid

impurities

≤0.002% heavy metals (as Pb)

ign. residue

≤0.1% (as SO4)

loss

≤0.5% loss on drying, 105 °C

color

white to faint beige

mp

163-166 °C
164-166 °C (lit.)

anion traces

chloride (Cl-): ≤100 mg/kg
sulfate (SO42-): ≤200 mg/kg

antibiotic activity spectrum

Gram-negative bacteria
Gram-positive bacteria

mode of action

DNA synthesis | interferes
enzyme | inhibits

Quality Level

100

Gene Information

human ... CA1(759), CA2(760), CA5A(763), CA5B(11238), CA9(768)
mouse ... Car13(71934), Car5a(12352)

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相关类别

Application

  • Study of new azo-azomethine derivatives of sulfanilamide: synthesis, characterization, spectroscopic, antimicrobial, antioxidant and anticancer activity：通过生成重氮盐反应物并与2-羟基-3-甲氧基苯甲醛偶联制备对氨基苯磺酰胺的新衍生物，研究它们的潜在抗菌、抗氧化和抗癌活性(HS Al-Atbi, IJ Al-Assadi, et al., 2020)。

General description

化学结构：磺胺
磺胺（对氨基苯磺酰胺）是一种对氨基取代的苯磺酰胺。其邻-单和二碘衍生物已被合成。

Other Notes

保存于密闭容器内，置于干燥通风处。

Packaging

33626-100G; 33626-6X100G

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCN7194
BCCL2542
BCCK0524
BCCH6172
BCCJ6525

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Caroline A Dobbin et al.
Journal of immunology (Baltimore, Md. : 1950), 169(2), 958-965 (2002-07-05)
We propose that the 70-kDa heat shock protein (HSP70) protects virulent Toxoplasma gondii from the effects of the host by immunomodulation. This hypothesis was tested using quercetin and antisense oligonucleotides targeting the start codon of the virulent T. gondii HSP70
The Iodination of p-Aminobenzenesulfonamide and Some Symmetrical Azobenzenesulfonamides.
Scudi JV.
Journal of the American Chemical Society, 59(8), 1480-1483 (1937)
Traci L Ness et al.
Journal of immunology (Baltimore, Md. : 1950), 173(11), 6938-6948 (2004-11-24)
CCR1 has previously been shown to play important roles in leukocyte trafficking, pathogen clearance, and the type 1/type 2 cytokine balance, although very little is known about its role in the host response during sepsis. In a cecal ligation and
Joseph A Hollenbaugh et al.
Journal of immunology (Baltimore, Md. : 1950), 177(5), 3004-3011 (2006-08-22)
We previously reported that IFN-gamma secreted by donor cytotoxic T cell 1 (Tc1) cells was the most important factor in promoting EG7 (an OVA transfection the EL4 thymoma) rejection in mice. In this study, we show that the ability of
Edward E Knaus et al.
Bioorganic & medicinal chemistry letters, 21(19), 5892-5896 (2011-08-20)
A series of compounds incorporating regioisomeric phenylethynylbenzenesulfonamide moieties has been investigated for the inhibition of four human carbonic anhydrase (hCA, EC 4.2.1.1) isoforms, hCA I, II, IX and XII. Inhibition between the low nanomolar to the milliomolar range has been
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