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Merck
CN

33626

Sigma-Aldrich

对氨基苯磺酰胺

≥98% (calc. to the dried substance), solid, purum p.a.

别名:

对氨基苯磺酰胺

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关于此项目

线性分子式:
H2NC6H4SO2NH2
化学文摘社编号:
63-74-1
分子量:
172.20
Beilstein:
511852
EC 号:
200-563-4
MDL编号:
MFCD00007939
UNSPSC代码:
12352100
eCl@ss:
39093202
PubChem化学物质编号:
57648871
NACRES:
NA.21

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产品名称

对氨基苯磺酰胺, puriss. p.a., ≥98% (calc. to the dried substance)

等级

puriss. p.a.

质量水平

100

方案

≥98% (calc. to the dried substance)

表单

solid

杂质

≤0.002% heavy metals (as Pb)

灼烧残渣

≤0.1% (as SO4)

缺失

≤0.5% loss on drying, 105 °C

颜色

white to faint beige

mp

163-166 °C
164-166 °C (lit.)

痕量阴离子

chloride (Cl-): ≤100 mg/kg
sulfate (SO42-): ≤200 mg/kg

抗生素抗菌谱

Gram-negative bacteria
Gram-positive bacteria

作用机制

DNA synthesis | interferes
enzyme | inhibits

SMILES字符串

Nc1ccc(cc1)S(N)(=O)=O

InChI

1S/C6H8N2O2S/c7-5-1-3-6(4-2-5)11(8,9)10/h1-4H,7H2,(H2,8,9,10)

InChI key

FDDDEECHVMSUSB-UHFFFAOYSA-N

基因信息

human ... CA1(759), CA2(760), CA5A(763), CA5B(11238), CA9(768)
mouse ... Car13(71934), Car5a(12352)

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相关类别

一般描述

化学结构：磺胺
磺胺（对氨基苯磺酰胺）是一种对氨基取代的苯磺酰胺。其邻-单和二碘衍生物已被合成。

应用

  • Study of new azo-azomethine derivatives of sulfanilamide: synthesis, characterization, spectroscopic, antimicrobial, antioxidant and anticancer activity：通过生成重氮盐反应物并与2-羟基-3-甲氧基苯甲醛偶联制备对氨基苯磺酰胺的新衍生物，研究它们的潜在抗菌、抗氧化和抗癌活性(HS Al-Atbi, IJ Al-Assadi, et al., 2020)。

包装

33626-100G; 33626-6X100G

其他说明

保存于密闭容器内，置于干燥通风处。

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCN7194
BCCL2542
BCCK0524
BCCH6172
BCCJ6525

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Scudi JV.
Journal of the American Chemical Society, 59(8), 1480-1483 (1937)
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CCR1 has previously been shown to play important roles in leukocyte trafficking, pathogen clearance, and the type 1/type 2 cytokine balance, although very little is known about its role in the host response during sepsis. In a cecal ligation and
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We propose that the 70-kDa heat shock protein (HSP70) protects virulent Toxoplasma gondii from the effects of the host by immunomodulation. This hypothesis was tested using quercetin and antisense oligonucleotides targeting the start codon of the virulent T. gondii HSP70
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Journal of medicinal chemistry, 53(2), 850-854 (2009-12-24)
Coumarins constitute a general and totally new class of inhibitors of the zinc enzyme carbonic anhydrase (CA, EC 4.2.1.1), binding at the entrance of the active site cavity. We report here that the coumarin-binding site in CAs may interact with
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