33816
妥曲珠利砜
VETRANAL®, analytical standard
别名:
1-甲基-3-{3-甲基-4-[4-(三氟甲基磺酰)苯氧基]苯基}-1,3,5-三嗪-2,4,6(1H,3H,5H)-三酮
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关于此项目
经验公式（希尔记法）:
C18H14F3N3O6S
化学文摘社编号:
分子量:
457.38
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
等级
analytical standard
质量水平
产品线
VETRANAL®
保质期
limited shelf life, expiry date on the label
技术
HPLC: suitable
gas chromatography (GC): suitable
应用
forensics and toxicology
pharmaceutical (small molecule)
veterinary
包装形式
neat
SMILES字符串
CN1C(=O)NC(=O)N(C1=O)c2ccc(Oc3ccc(cc3)S(=O)(=O)C(F)(F)F)c(C)c2
InChI
1S/C18H14F3N3O6S/c1-10-9-11(24-16(26)22-15(25)23(2)17(24)27)3-8-14(10)30-12-4-6-13(7-5-12)31(28,29)18(19,20)21/h3-9H,1-2H3,(H,22,25,26)
InChI key
VBUNOIXRZNJNAD-UHFFFAOYSA-N
一般描述
Toltrazuril sulfone is an antiprotozoal agent, which belongs to the group of triazines. It is highly effective against apicomplexan group of organisms.
应用
Commission Regulation (EU) No 37/2010 of 22 December 2009 on pharmacologically active substances and their classification regarding maximum residue limits in foodstuffs of animal origin
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Toltrazuril sulfone may be used as a reference standard in the determination of toltrazuril sulfone in food samples using fast liquid chromatography coupled with tandem mass spectrometry (LC-MS-MS).
其他说明
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
法律信息
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
11 - Combustible Solids
WGK
WGK 3
个人防护装备
Eyeshields, Gloves, type N95 (US)
Pharmacokinetics of toltrazuril and its metabolites, toltrazuril sulfoxide and toltrazuril sulfone, after a single oral administration to pigs.
Lim HJ, et al.
The Journal of Veterinary Medical Science, 72(8), 1085-1087 (2010)
Detection, quantifications and pharmacokinetics of toltrazuril sulfone ([TM="Ponazuril"]) in cattle.
Dirikolu L, et al.
Journal of Veterinary Pharmacology and Therapeutics, 32(3), 280-288 (2009)
Anna Martínez-Villalba et al.
Analytical and bioanalytical chemistry, 397(7), 2893-2901 (2010-07-27)
In this work a fast liquid chromatography (LC)-tandem mass spectrometry (MS/MS) method was developed for the analysis of toltrazuril, a coccidiostatic drug, and its metabolites in meat food products. The applicability of atmospheric pressure chemical ionization (APCI) and heated electrospray
Janis Rusko et al.
Journal of pharmaceutical and biomedical analysis, 164, 402-412 (2018-11-16)
A new sensitive and selective multi-residue method based on liquid chromatography - Orbitrap high resolution mass spectrometry (LC-Orbitrap-HRMS) was developed and validated for the determination of 17 anticoccidials in poultry and eggs. Instrumental parameters were optimized by the means of
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