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Merck
CN

33823

癸氧喹酯

VETRANAL®, analytical standard

别名:

6-癸氧基-7-乙氧基-4-羟基-3-喹啉羧酸乙酯

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关于此项目

经验公式(希尔记法):
C24H35NO5
化学文摘社编号:
分子量:
417.54
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
242-389-1
MDL number:
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InChI key

JHAYEQICABJSTP-UHFFFAOYSA-N

InChI

1S/C24H35NO5/c1-4-7-8-9-10-11-12-13-14-30-21-15-18-20(16-22(21)28-5-2)25-17-19(23(18)26)24(27)29-6-3/h15-17H,4-14H2,1-3H3,(H,25,26)

SMILES string

CCCCCCCCCCOc1cc2c(O)c(cnc2cc1OCC)C(=O)OCC

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

Quality Level

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General description

Decoquinate is a quinolone coccidiostat used in poultry, to retard the growth of coccidian parasites and can also show activity against Plasmodium falciparum parasite, which causes malaria in humans.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

hcodes

Hazard Classifications

Aquatic Chronic 4

存储类别

11 - Combustible Solids

wgk

WGK 3

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Tracing the emergence of drug-resistance in coccidia (Eimeria spp.) of commercial broiler flocks medicated with decoquinate for the first time in the United Kingdom
Williams.B.R
Veterinary Parasitology, 135, 1-14 (2006)
Questions limitation in treatment of hepatozoonosis.
Nancy Vincent-Johnson
Journal of the American Veterinary Medical Association, 226(12), 1979-1979 (2005-07-02)
R B Williams
International journal for parasitology, 27(1), 101-111 (1997-01-01)
The anticoccidial mode of action of quinolones (6-decyloxy-4-hydroxyquinoline-3-carboxylates) against Eimeria tenella and E. acervulina in chickens has been investigated, using decoquinate and M&B 15,584 as examples. The well known static effect on sporozoites of relatively high continuous drug concentrations in
R B Williams
Veterinary parasitology, 135(1), 1-14 (2005-11-18)
Decoquinate is a quinolone coccidiostat introduced during 1967 as an in-feed prophylactic for broiler chickens. Despite early drug-resistance problems and its age, the drug is still used commercially worldwide. Decoquinate here serves as a valuable model in a field study
Z-Y Wang et al.
Journal of veterinary pharmacology and therapeutics, 36(2), 116-121 (2012-03-03)
A rapid, sensitive, and reliable high-performance liquid chromatography tandem mass spectrometry (LC-MS/MS) method was developed and validated for the analysis of decoquinate in chicken tissues. The compounds were extracted using acetonitrile by liquid-liquid extraction (LLE) and purified with an Oasis(™)

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