33823
癸氧喹酯
VETRANAL®, analytical standard
别名:
6-癸氧基-7-乙氧基-4-羟基-3-喹啉羧酸乙酯
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关于此项目
经验公式（希尔记法）:
C24H35NO5
化学文摘社编号:
分子量:
417.54
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
242-389-1
MDL number:
产品名称
癸氧喹酯, VETRANAL®, analytical standard
InChI key
JHAYEQICABJSTP-UHFFFAOYSA-N
InChI
1S/C24H35NO5/c1-4-7-8-9-10-11-12-13-14-30-21-15-18-20(16-22(21)28-5-2)25-17-19(23(18)26)24(27)29-6-3/h15-17H,4-14H2,1-3H3,(H,25,26)
SMILES string
CCCCCCCCCCOc1cc2c(O)c(cnc2cc1OCC)C(=O)OCC
grade
analytical standard
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
format
neat
Quality Level
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Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
General description
Decoquinate is a quinolone coccidiostat used in poultry, to retard the growth of coccidian parasites and can also show activity against Plasmodium falciparum parasite, which causes malaria in humans.
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
hcodes
pcodes
Hazard Classifications
Aquatic Chronic 4
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
Eyeshields, Gloves, type N95 (US)
M A Taylor et al.
Journal of veterinary pharmacology and therapeutics, 35(5), 417-427 (2012-06-26)
Decoquinate is a quinolone derivative that has been used for over 20 years in the control of coccidiosis in domestic ruminants. Decoquinate treats coccidiosis in lambs and calves and prevents coccidiosis in lambs when administered in feed at a dosage
D S Lindsay et al.
Veterinary parasitology, 68(1-2), 35-40 (1997-01-01)
Neospora caninum is a major cause of abortion in dairy cattle in the United States and other countries. Abortions and neonatal mortality also occur in other ruminant species. Decoquinate is an anticoccidial that is approved for use in cattle and
D S Lindsay et al.
Veterinary parasitology, 89(4), 307-311 (2000-05-09)
Cryptosporidium parvum is an apicomplexan parasite that is an important cause of diarrhea in neonatal calves and humans. No treatment is currently available for neonatal calves. We have recently learned from colleagues in the pharmaceutical industry that dairy practitioners are
Tae-Gyu Nam et al.
ACS chemical biology, 6(11), 1214-1222 (2011-08-27)
Decoquinate has single-digit nanomolar activity against in vitro blood stage Plasmodium falciparum parasites, the causative agent of human malaria. In vitro evolution of decoquinate-resistant parasites and subsequent comparative genomic analysis to the drug-sensitive parental strain revealed resistance was conferred by
Medicating feeds for early lambing ewes.
Neville Suttle
The Veterinary record, 170(6), 161-161 (2012-02-15)
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