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33864

替米可新

VETRANAL®, analytical standard, mix of isomers

别名:

20-脱氧-20-(3,5-二甲基-1-呱啶基)脱红霉糖泰乐菌素

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关于此项目

经验公式（希尔记法）:
C46H80N2O13
分子量:
869.13
NACRES:
NA.24
PubChem Substance ID:
329754677
UNSPSC Code:
41116107
MDL number:
MFCD19705582
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grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

CC1OC(OCC(C(CC)O2)/C=C(/C=C/C(C(C)CC(CCN3CC(C)CC(C)C3)C(OC4OC(C)C(O)C(N(C)C)C4O)C(C)C(O)CC2=O)=O)C)C(OC)C(OC)C1O

InChI

1S/C46H80N2O13/c1-13-36-33(24-57-46-44(56-12)43(55-11)40(53)31(8)59-46)19-25(2)14-15-34(49)28(5)20-32(16-17-48-22-26(3)18-27(4)23-48)42(29(6)35(50)21-37(51)60-36)61-45-41(54)38(47(9)10)39(52)30(7)58-45/h14-15,19,26-33,35-36,38-46,50,52-54H,13,16-18,20-24H2,1-12H3/b15-14+,25-19+/t26-,27+,28-,29+,30-,31-,32+,33-,35-,36-,38+,39-,40-,41-,42-,43-,44-,45+,46-/m1/s1

InChI key

JTSDBFGMPLKDCD-XVFHVFLVSA-N

General description

Tilmicosin is a semisynthetic macrolide antibiotic, with broad spectrum activity towards Mycoplasma spp., Pasteurella spp., and various gram-positive organisms in animals.

Application

Tilmicosin may be used as a reference standard for the determination of the analyte in chicken, swine, cattle, sheep tissues and milk samples using liquid chromatography with ultraviolet detection (LC-UV).
Commission Regulation (EU) No 37/2010 of 22 December 2009 on pharmacologically active substances and their classification regarding maximum residue limits in foodstuffs of animal origin
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2

target_organs

Cardio-vascular system

存储类别

11 - Combustible Solids

wgk

WGK 3

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCN6594
BCCM4665
BCCG2736
BCCD7299
BCCB4507

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Shuyu Xie et al.
Particle and fibre toxicology, 8, 33-33 (2011-11-22)
Our previous studies demonstrated that tilmicosin-loaded hydrogenated castor oil solid lipid nanoparticles (Til-HCO-SLN) are a promising formulation for enhanced pharmacological activity and therapeutic efficacy in veterinary use. The purpose of this work was to evaluate the acute toxicity of Til-HCO-SLN.
Determination of tilmicosin residues in cow and sheep milk by liquid chromatography.
Stobba-Wiley.MC and Readnour.SR
Journal of AOAC (Association of Official Analytical Chemists) International, 83(3), 555-562 (2000)
Dapeng Peng et al.
Journal of agricultural and food chemistry, 60(1), 44-51 (2011-12-06)
Incorrect use of tylosin and tilmicosin could result in allergy and select resistance. To monitor the illegal use of these antibiotics in animals, a monoclonal-based indirect competitive enzyme-linked immunosorbent assay (ic-ELISA) has been established. Several haptens were synthesized and conjugated
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全球贸易项目编号

货号GTIN
33864-100MG-R04061826745007