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About This Item
经验公式（希尔记法）:
C22H17ClN2
CAS Number:
分子量:
344.84
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
等级
analytical standard
产品线
VETRANAL®
保质期
limited shelf life, expiry date on the label
技术
HPLC: suitable
gas chromatography (GC): suitable
抗生素抗菌谱
fungi
应用
agriculture
environmental
包装形式
neat
作用机制
protein synthesis | interferes
SMILES字符串
Clc1ccccc1C(c2ccccc2)(c3ccccc3)n4ccnc4
InChI
1S/C22H17ClN2/c23-21-14-8-7-13-20(21)22(25-16-15-24-17-25,18-9-3-1-4-10-18)19-11-5-2-6-12-19/h1-17H
InChI key
VNFPBHJOKIVQEB-UHFFFAOYSA-N
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一般描述
Clotrimazole, a non-toxic, systemic, imidazole derivative with broad-spectrum antimycotic activity, is primarily used in the treatment of oropharyngeal candidiasis.
Its mode of action involves the inhibition of ergosterol synthesis, which leads to structural and functional damage of the cell membrane.
应用
Clotrimazole may be used as a reference standard for the determination of the analyte in topical creams and ear drops by reversed-phase high-performance liquid chromatographic (RP-HPLC) method.
Clotrimazole may be used as an analytical reference standard for the determination of the analyte in:
- Milk samples using solid-phase extraction followed by high-performance liquid chromatography (SPE-HPLC).
- Environmental water samples using dispersive liquid-liquid microextraction followed by high-performance liquid chromatography with tandem mass spectrometry (HPLC-MS/MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
法律信息
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
警示用语：
Warning
危险分类
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2
储存分类代码
11 - Combustible Solids
WGK
WGK 3
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
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