33979
双氯苄氨胍 盐酸盐
VETRANAL®, analytical standard
别名:
1,3-双[(4-氯苯亚甲基)氨基]胍 单盐酸盐
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经验公式（希尔记法）:
C15H13Cl2N5 · HCl
化学文摘社编号:
分子量:
370.66
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
247-307-8
MDL number:
产品名称
双氯苄氨胍 盐酸盐, VETRANAL®, analytical standard
InChI key
LTWIBTYLSRDGHP-HCURTGQUSA-N
InChI
1S/C15H13Cl2N5.ClH/c16-13-5-1-11(2-6-13)9-19-21-15(18)22-20-10-12-3-7-14(17)8-4-12;/h1-10H,(H3,18,21,22);1H/b19-9+,20-10+;
SMILES string
Cl[H].Clc1ccc(cc1)\C=N\NC(=N)N\N=C\c2ccc(Cl)cc2
grade
analytical standard
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
format
neat
Quality Level
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Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Robenidine hydrochloride has been used as a reference standard in the determination of robenidine hydrochloride in eggs using online solid-phase extraction with liquid chromatography coupled with tandem mass spectrometry (SPE-LC-MS/MS).
General description
Robenidine hydrochloride is a coccidiostat and antibiotic, used in controlling coccidiosis.
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
R Brun et al.
Tropical medicine & international health : TM & IH, 6(5), 362-368 (2001-05-12)
CGP 40 215 is an inhibitor of S-adenosylmethionine decarboxylase, a key enzyme in trypanosomal polyamine biosynthesis. It is highly active against Trypanosoma brucei rhodesiense and T. b. gambiense in vitro and in the corresponding rodent models, and therefore was a
Martin Hansen et al.
Environmental pollution (Barking, Essex : 1987), 157(2), 474-480 (2008-11-04)
The antibacterial potency of eight anticoccidial drugs was tested in a soil bacteria bioassay (pour plate method), EC(50)-values between 2.4 and 19.6 microM were obtained; however, one compound, nicarbazin exhibited an EC(50)-value above the maximum tested concentration (21 microM, 9.1
Robin Das Gupta et al.
Antimicrobial agents and chemotherapy, 49(7), 2857-2864 (2005-06-28)
The intraerythrocytic development of Plasmodium falciparum correlates with increasing levels of the polyamines putrescine, spermidine, and spermine in the infected red blood cells; and compartmental analyses revealed that the majority is associated with the parasite. Since depletion of cellular polyamines
Binh Nguyen et al.
Biophysical journal, 90(4), 1319-1328 (2005-11-22)
The energetics for binding of a diphenyl diamidine antitrypanosomal agent CGP 40215A to DNA have been studied by spectroscopy, isothermal titration calorimetry, and surface plasmon resonance biosensor methods. Both amidines are positively charged under experimental conditions, but the linking group
J E Peeters et al.
Veterinary parasitology, 29(4), 327-331 (1988-10-01)
Caecal samples were collected from 751 domestic rabbits of various origin and from 1229 diarrhoeic rabbits issued from 61 commercial rabbitries. They were screened for coccidiosis. In 1982, the year of introduction of the anticoccidial robenidine in commercial rabbit feeds
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