33998
醋酸美伦孕酮
VETRANAL®, analytical standard
别名:
17α-乙酰氧基-6-甲基-16-亚甲基-4,6-孕甾二烯-3,20-二酮
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关于此项目
经验公式（希尔记法）:
C25H32O4
化学文摘社编号:
分子量:
396.52
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
220-859-7
Beilstein/REAXYS Number:
2066919
MDL number:
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
InChI
1S/C25H32O4/c1-14-11-19-20(23(5)9-7-18(28)13-21(14)23)8-10-24(6)22(19)12-15(2)25(24,16(3)26)29-17(4)27/h11,13,19-20,22H,2,7-10,12H2,1,3-6H3/t19-,20+,22+,23-,24+,25+/m1/s1
InChI key
UDKABVSQKJNZBH-DWNQPYOZSA-N
SMILES string
[H][C@]12CC[C@@]3(C)[C@@]([H])(CC(=C)[C@]3(OC(C)=O)C(C)=O)[C@]1([H])C=C(C)C4=CC(=O)CC[C@]24C
grade
analytical standard
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
mp
202-204 °C (lit.)
application(s)
clinical testing
format
neat
Quality Level
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General description
Melengestrol acetate belongs to the family of hormones. This acetylgestagen compound is known to elicit a gestagenic effect in vivo.
Application
Melengestrol acetate may be used as a reference standard for the determination of the analyte in:
- Milk using turborFlow online solid phase extraction (SPE) combined with liquid chromatography-tandem mass spectrometry (LC-MS/MS).
- Kidney fats by ultra-performance convergence chromatography-tandem mass spectrometry.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Warning
hcodes
Hazard Classifications
Repr. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
涉药品监管产品
此项目有
Simultaneous determination of seven gestagens in kidney fats by Ultra Performance Convergence Chromatography tandem mass spectrometry.
Tao Y, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 988, 143-148 (2015)
G A Perry et al.
Theriogenology, 71(5), 775-779 (2008-11-14)
Treatment with GnRH at the onset of standing estrus increased pregnancy percentages and circulating concentrations of progesterone in repeat breeder dairy cows. The objective of this study was to determine the effect of treatment with GnRH at AI on concentrations
D R Eborn et al.
Journal of animal science, 91(2), 666-672 (2012-12-12)
Two experiments were conducted over 3 yr to determine pregnancy rates in beef heifers after a timed AI in response to the 7-11 Synch protocol. In Exp. 1, 179 heifers were either fed melengestrol acetate (MGA; 7-11 Synch) or given
D McAloose et al.
Veterinary pathology, 44(3), 320-326 (2007-05-11)
Melengestrol acetate (MGA), a potent synthetic progestin, has been used as a contraceptive in zoo felids since 1975. Mammary gland carcinomas have been linked to MGA treatment in zoo felids, but the histologic features of these tumors and steroid receptor
Madis Lõhmus et al.
Analytica chimica acta, 586(1-2), 233-238 (2007-03-28)
The use of gestagens in animal fattening is prohibited within the European Union. Recently, the use of spectrometric methods for the detection and confirmation of banned substances was made obligatory. Therefore, conventional high-performance liquid chromatographic (HPLC) methods have been superseded.
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